Patents by Inventor Isabel Najera

Isabel Najera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4?-substituted nucleoside derivatives as inhibitors of HCV RNA replication.
    Patent number: 6784166
    Abstract: The present invention relates to the use of nucleoside derivatives of formula I wherein B signifies a 9-purinyl residue B1 of formula or a 1-pyrimidyl residue B2 of formula wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: August 31, 2004
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Rene Robert Devos, Christopher John Hobbs, Wen Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera, Nobuo Shimma, Takuo Tsukuda
  • Anti-HCV nucleoside derivatives
    Publication number: 20040110718
    Abstract: The present invention comprises novel and known purine and pyrimidine nucleoside derivatives which have been discovered to be active against hepatitis C virus (HCV). The use of these derivatives for the treatment of HCV infection is claimed as are the novel nucleoside derivatives disclosed herein.
    Type: Application
    Filed: October 3, 2003
    Publication date: June 10, 2004
    Inventors: Rene Devos, Brian William Dymock, Christopher John Hobbs, Wen-Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera, Nobuo Shimma, Takuo Tsukuda
  • 4'-substituted nucleoside derivatives as inhibitors of HCV RNA replication
    Publication number: 20030236216
    Abstract: The present invention relates to the use of nucleoside derivatives of formula I 1
    Type: Application
    Filed: June 11, 2002
    Publication date: December 25, 2003
    Inventors: Rene Robert Devos, Christopher John Hobbs, Wen Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera, Nobuo Shimma, Takuo Tsukuda
  • Anti-HCV nucleoside derivatives
    Patent number: 6660721
    Abstract: The present invention comprises nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention discloses the novel use of known 2′-deoxy-2′-fluoro nucleoside derivatives as inhibitors of hepatitis C virus (HCV) RNA replication and pharmaceutical compositions of such compounds. The compounds of this invention have potential use as therapeutic agents for the treatment of HCV infections.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: December 9, 2003
    Assignee: Hoffmann-la Roche Inc.
    Inventors: Rene Robert Devos, Christopher John Hobbs, Wen-Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera
  • Anti-HCV nucleoside derivatives
    Publication number: 20030083307
    Abstract: The present invention comprises nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention discloses the novel use of known 2′-deoxy-2′-fluoro nucleoside derivatives as inhibitors of hepatitis C virus (HCV) RNA replication and pharmaceutical compositions of such compounds. The compounds of this invention have potential use as therapeutic agents for the treatment of HCV infections.
    Type: Application
    Filed: March 26, 2002
    Publication date: May 1, 2003
    Inventors: Rene Robert Devos, Christopher John Hobbs, Wen-Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera
  • Anti-HCV nucleoside derivatives
    Publication number: 20030008841
    Abstract: The present invention comprises novel and known purine and pyrimidine nucleoside derivatives which have been discovered to be active against hepatitis C virus (HCV). The use of these derivatives for the treatment of HCV infection is claimed as are the novel nucleoside derivatives disclosed herein.
    Type: Application
    Filed: August 7, 2001
    Publication date: January 9, 2003
    Inventors: Rene Devos, Brian William Dymock, Christopher John Hobbs, Wen-Rong Jiang, Joseph Armstrong Martin, John Herbert Merrett, Isabel Najera, Nobuo Shimma, Takuo Tsukuda