Patents by Inventor ISABELLE CAROLINE LE POOLE

ISABELLE CAROLINE LE POOLE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HSP70-Based Treatment for Autoimmune Diseases and Cancer
    Publication number: 20110028403
    Abstract: A non-natural HSP70 activating region that activates dendritic cells. Polypeptides that bind to the HSP70 activating region can be used to treat autoimmune diseases, such as vitiligo, by binding to HSP70 and preventing HSP70 form activating dendritic cells. The HSP70 binders can be constructed in the form of fusions proteins with a trimerizing structural element that may associate to form a trimeric complex. Pharmaceutical compositions and methods for treating vitiligo using the HSP70 binding proteins, fusion proteins and complexes.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 3, 2011
    Inventors: ISABELLE CAROLINE LE POOLE, JOSEPHUS DIRK NIELAND, THOR LAS HOLTET