Patents by Inventor Isabelle Cornut

Isabelle Cornut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multimeric apoprotein agonists
    Patent number: 7566695
    Abstract: The present invention provides multimeric apoprotein agonists. Pharmaceutical compositions which include a multimeric apoprotein agonist and a pharmaceutically acceptable carrier, excipient or diluent are also provided. These pharmaceutical are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: July 28, 2009
    Assignee: Pfizer Inc.
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20080058270
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: February 9, 2007
    Publication date: March 6, 2008
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Gene Therapy Approaches to Supply Apolipoprotein A-I Agonists and Their Use to Treat Dyslipidemic Disorder
    Publication number: 20080050351
    Abstract: The invention relates to genetic approaches to supply nucleotide sequences encoding modified forms of the native forms of apolipoprotein A-I (ApoA-I): mature ApoA-I, reproApoA-I and proApoA-I; including native ApoA-I modified to contain ApoA-I agonists, peptides which mimic the activity of ApoA-I; ApoA-I superagonists, peptides which exceed the activity of native ApoA-I; and modified native ApoA-I having one or more amphipathic helices replaced by the nucleotide sequences of one or more ApoA-I agonists; for the treatment of disorders associated with dyslipoproteinemia, including cardiovascular disease, atherosclerosis, restenosis, hyperlipidemia, and other disorders such as septic shock.
    Type: Application
    Filed: June 18, 2007
    Publication date: February 28, 2008
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz, Jean Dufourcq
  • Pharmaceutical compositions of apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 7312190
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: December 25, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq
  • Multimeric Apo A-I agonist compounds
    Patent number: 7307058
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: December 11, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 7273848
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: September 25, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz
  • Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 7250407
    Abstract: The invention relates to genetic approaches to supply nucleotide sequences encoding modified forms of the native forms of apolipoprotein A-I (ApoA-I): mature ApoA-I, preproApoA-I and proApoA-I; including native ApoA-I modified to contain ApoA-I agonists, peptides which mimic the activity of ApoA-I; ApoA-I superagonists, peptides which exceed the activity of native ApoA-I; and modified native ApoA-I having one or more amphipathic helices replaced by the nucleotide sequences of one or more ApoA-I agonists; for the treatment of disorders associated with dyslipoproteinemia, including cardiovascular disease, atherosclerosis, restenosis, hyperlipidemia, and other disorders such as septic shock.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: July 31, 2007
    Assignee: Pfizer Inc.
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 7211565
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: May 1, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Apolipoprotein A-L agonists and their use to treat dyslipidemic disorders
    Patent number: 7189689
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: March 13, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 7157425
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: January 2, 2007
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20060252694
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: June 23, 2006
    Publication date: November 9, 2006
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Multimeric Apo A-I agonist compounds
    Publication number: 20050215467
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: November 17, 2003
    Publication date: September 29, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20050203284
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: March 15, 2002
    Publication date: September 15, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20050148513
    Abstract: The invention relates to genetic approaches to supply nucleotide sequences encoding modified forms of the native forms of apolipoprotein A-I (ApoA-I): mature ApoA-I, preproApoA-I and proApoA-I; including native ApoA-I modified to contain ApoA-I agonists, peptides which mimic the activity of ApoA-I; ApoA-I superagonists, peptides which exceed the activity of native ApoA-I; and modified native ApoA-I having one or more amphipathic helices replaced by the nucleotide sequences of one or more ApoA-I agonists; for the treatment of disorders associated with dyslipoproteinemia, including cardiovascular disease, atherosclerosis, restenosis, hyperlipidemia, and other disorders such as septic shock.
    Type: Application
    Filed: November 16, 2004
    Publication date: July 7, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 6900177
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: May 31, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20050080013
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: September 8, 2004
    Publication date: April 14, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Patent number: 6844327
    Abstract: The invention relates to genetic approaches to supply nucleotide sequences encoding modified forms of the native forms of apolipoprotein A-I (ApoA-I): mature ApoA-I, preproApoA-I and proApoA-I; including native ApoA-I modified to contain ApoA-I agonists, peptides which mimic the activity of ApoA-I; ApoA-I superagonists, peptides which exceed the activity of native ApoA-I; and modified native ApoA-I having one or more amphipathic helices replaced by the nucleotide sequences of one or more ApoA-I agonists; for the treatment of disorders associated with dyslipoproteinemia, including cardiovascular disease, atherosclerosis, restenosis, hyperlipidemia, and other disorders such as septic shock.
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: January 18, 2005
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq
  • Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
    Publication number: 20040198662
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: March 15, 2004
    Publication date: October 7, 2004
    Applicant: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz
  • Multimeric Apo A-I agonist compounds
    Publication number: 20040181034
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Application
    Filed: March 15, 2004
    Publication date: September 16, 2004
    Applicant: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Buttner, Isabelle Cornut, Gunther Metz, Jean Dufourcq
  • Multimeric Apoa-I agonist compounds
    Patent number: 6753313
    Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: June 22, 2004
    Inventors: Jean-Louis Dasseux, Renate Sekul, Klaus Büttner, Isabelle Cornut, Günther Metz, Jean Dufourcq