Abstract: A model selection method is provided for choosing the number of clusters, or more generally the parameters of a clustering algorithm. The algorithm is based on comparing the similarity between pairs of clustering runs on sub-samples or other perturbations of the data. High pairwise similarities show that the clustering represents a stable pattern in the data. The method is applicable to any clustering algorithm, and can also detect lack of structure. We show results on artificial and real data using a hierarchical clustering algorithm.

Abstract: A network-based system is provided for performing data analysis services using a support vector machine for analyzing data received from a remote user connected to the network. The user transmits a data set to be analyzed and along with an account identifier that allows the analysis service provider to collect payment for the processing services. Once payment has been confirmed, the service provider's server transmits the analysis results to the remote user.

Abstract: In a pre-processing step prior to training a learning machine, pre-processing includes reducing the quantity of features to be processed using feature selection methods selected from the group consisting of recursive feature elimination (RFE), minimizing the number of non-zero parameters of the system (l0-norm minimization), evaluation of cost function to identify a subset of features that are compatible with constraints imposed by the learning set, unbalanced correlation score, transductive feature selection and single feature using margin-based ranking. The features remaining after feature selection are then used to train a learning machine for purposes of pattern classification, regression, clustering and/or novelty detection.

Abstract: A computer system for performing data analysis services using a support vector machine for analyzing data received from a remote source on a distributed network includes a server in communication with the distributed network for receiving a data set and a financial account identifier associated with the remote source. The server communicates over the distributed network with a financial institution to receive funds from a financial account identified by the financial account identifier. A processor receives one or more data sets from the remote source and pre-processes the data to enhance meaning within the data set. The pre-processed data is used to train and test a support vector machine for recognizing patterns within the data. Live data is processed using the trained and tested support vector machine to generate an output which is transmitted to the remote source after the server confirms that payment for the data processing service has been received.

Abstract: Biomarkers are identified by analyzing gene expression data using support vector machines (SVM), recursive feature elimination (RFE) and/or linear ridge regression classifiers to rank genes according to their ability to separate prostate cancer from normal tissue. Proteins expressed by identified genes are detected in patient samples to screen, predict and monitor prostate cancer.

Abstract: Biomarkers are identified by analyzing gene expression data using support vector machines (SVM) to rank genes according to their ability to separate prostate cancer from normal tissue. Proteins expressed by identified genes are detected in patient samples to screen, predict and monitor prostate cancer.