Patents by Inventor Isabelle Henry

Isabelle Henry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10717647
    Abstract: A sensing platform includes a substrate, an array of wells formed in the substrate, and sorted nanoparticles filling in the array of wells such that each well contains a single sorted nanoparticle, wherein the sorted nanoparticles are in a cluster state.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: July 21, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Timothy P. Tyler, Anne-Isabelle Henry, Richard P. Van Duyne, Mark C. Hersam
  • Publication number: 20180050905
    Abstract: A sensing platform includes a substrate, an array of wells formed in the substrate, and sorted nanoparticles filling in the array of wells such that each well contains a single sorted nanoparticle, wherein the sorted nanoparticles are in a cluster state.
    Type: Application
    Filed: September 26, 2017
    Publication date: February 22, 2018
    Inventors: Timothy P. Tyler, Anne-Isabelle Henry, Richard P. Van Duyne, Mark C. Hersam
  • Patent number: 9802818
    Abstract: In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
    Type: Grant
    Filed: May 1, 2012
    Date of Patent: October 31, 2017
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Timothy P. Tyler, Anne-Isabelle Henry, Richard P. Van Duyne, Mark C. Hersam
  • Publication number: 20120281213
    Abstract: In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
    Type: Application
    Filed: May 1, 2012
    Publication date: November 8, 2012
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: TIMOTHY P. TYLER, ANNE-ISABELLE HENRY, RICHARD P. VAN DUYNE, MARK C. HERSAM
  • Publication number: 20040097439
    Abstract: The present invention is concerned with modified polynucleotides derived from a native gene and having a reduced or increased number of epigenetic control motifs, at the nucleotide level, as compared to the native gene. These polynucleotides are useful to study, increase and/or reduce genes expression, and to improve DNA vaccination methods. The present invention also relates to methods of using these modified polynucleotides in in vitro and in vivo expression systems.
    Type: Application
    Filed: June 6, 2002
    Publication date: May 20, 2004
    Inventors: Jean-Francois Nicolas, Isabelle Henry, Andre Choulika
  • Publication number: 20030100528
    Abstract: The present invention is concerned with modified polynucleotides derived from a native gene and having a reduced or increased number of epigenetic control motifs, at the nucleotide level, as compared to the native gene. These polynucleotides are useful to study, increase and/or reduce genes expression, and to improve DNA vaccination methods. The present invention also relates to methods of using these modified polynucleotides in in vitro and in vivo expression systems.
    Type: Application
    Filed: June 6, 2002
    Publication date: May 29, 2003
    Inventors: Jean-Francois Nicolas, Isabelle Henry, Andre Choulika