Patents by Inventor Isabelle Lucet

Isabelle Lucet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR INHIBITING NECROPTOSIS
    Publication number: 20170114025
    Abstract: The present invention relates to methods for inhibiting necroptosis; screening methods for identifying compounds which inhibit necroptosis; and compounds for the inhibition of necroptosis, which may be useful in the treatment of conditions associated with deregulated necroptosis.
    Type: Application
    Filed: May 15, 2015
    Publication date: April 27, 2017
    Inventors: Isabelle Lucet, Jean-Marc Garnier, James Michael Murphy, John Hendry Silke, Joanne Maree Hildebrand, John Thomas Feutrill, Anthony Nicholas Cuzzupe, Guillaume Laurent Lessene, Peter Edward Czabotar, Andrew Frederick Wilks, Pooja Sharma
  • Crystal structure of human Janus Kinase 2 (JAK2) and uses thereof
    Patent number: 7593820
    Abstract: The present invention relates to X-ray crystallography studies of a human Janus Kinase 2 (JAK2) domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to a inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: September 22, 2009
    Assignee: Cytopia Research Pty Ltd
    Inventors: Andrew Frederick Wilks, Christopher John Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Leanne Styles
  • Crystal structure and uses thereof
    Publication number: 20070276607
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: November 29, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070136005
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 14, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070136006
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 14, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070129896
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070129895
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070128709
    Abstract: The present invention relates to X-ray crystallography studies of a human Janus Kinase 2 (JAK2) domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles