Patents by Inventor Isabelle Noelle Constance Pilatte

Isabelle Noelle Constance Pilatte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
    Patent number: 7834025
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: November 16, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Patrick René Angibaud, Isabelle Noëlle Constance Pilatte
  • Inhibitors of histone deacetylase
    Patent number: 7816363
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Patrick René Angibaud, Isabelle Noëlle Constance Pilatte, Sven Franciscus Anna Van Brandt, Bruno Roux, Marc Gustaaf Celine Verdonck, Alexey Borisovich Dyatkin
  • Sulfonyl-Derivatives as Novel or Histone Deacetylase
    Publication number: 20100240639
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: April 13, 2010
    Publication date: September 23, 2010
    Inventors: Kristof Van Emelen, Janine Arts, Leo-Jacobus Jozef Backx, Hans Louis Jos De Winter, Sven Franciscus Anna Van Brandt, Mac Gustaaf Celine Verdonck, Lieven Meerpoel, Isabelle Noëlle Constance Pilatte, Virginie Sophie Poncelet, Alexey Borisovich Dyatkin, Jimmy Arnold Viviane Van heusden
  • SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20100234353
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: March 15, 2010
    Publication date: September 16, 2010
    Applicant: Janssen Pharmaceutica N.V.
    Inventors: Kristof Van Emelen, Leo Jacobus Jozef Backx, Sven Franciscus Anna Van Brandt, Patrick René Angibaud, Isabelle Noëlle Constance Pilatte, Marc Gustaaf Celine Verdonck, Hans Louis Jos De Winter, Jimmy Arnold Viviane Van Heusden
  • Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
    Patent number: 7767679
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: August 3, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Kristof Van Emelen, Leo Jacobus Jozef Backx, Sven Franciscus Anna Van Brandt, Patrick René Angibaud, Isabelle Noëlle Constance Pilatte, Marc Gustaaf Celine Verdonck, Hans Louis Jos De Winter, Jimmy Arnold Viviane Van heusden
  • Sulfonyl-derivatives as novel inhibitors of histone deacetylase
    Patent number: 7709487
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: May 4, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Kristof Van Emelen, Janine Arts, Leo Jacobus Jozef Backx, Hans Louis Jos De Winter, Sven Franciscus Anna Van Brandt, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Isabelle Noelle Constance Pilatte, Virginie Sophie Poncelet, Alexey Borisovich Dyatkin, Jimmy Arnold Viviane Van heusden
  • Sulfonyl-derivatives as novel inhibitors or histone deacetylase
    Patent number: 7704998
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: April 27, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Kristof Van Emelen, Janine Arts, Leo-Jacobus Jozef Backx, Hans Louis Jos De Winter, Sven Franciscus Anna Van Brandt, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Isabelle Noelle Constance Pilatte, Virginie Sophie Poncelet, Alexey Borisovich Dyatkin, Jimmy Arnold Viviane Van heusden
  • NEW INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20090170836
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: February 18, 2009
    Publication date: July 2, 2009
    Inventors: Patrick Rene Angibaud, Isabelle Noelle Constance Pilatte, Sven Franciscus Anna Van Brandt, Bruno Roux, Peter Ten Holte, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Alexey Borisovich Dyatkin
  • NEW INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20090170881
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: February 18, 2009
    Publication date: July 2, 2009
    Inventors: Patrick Rene Angibaud, Isabelle Noelle Constance Pilatte, Sven Franciscus Anna Van Brandt, Bruno Roux, Peter Ten Holte, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Alexey Borisovich Dyatkin
  • SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20090124646
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: July 25, 2005
    Publication date: May 14, 2009
    Applicant: Janssen Pharmaceutica N.V.
    Inventors: Marc Gustaaf Celine Verdonck, Patrick Rene Angibaud, Bruno Roux, Isabelle Noelle Constance Pilatte, Peter Ten Holte, Janine Arts, Kristof Van Emelen
  • Aminophenyl Derivatives as Novel Inhibitors of Histone Deacetylase
    Publication number: 20090018152
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 16, 2007
    Publication date: January 15, 2009
    Inventors: Patrick Rene Angibaud, Isabelle Noelle Constance Pilatte, Bruno Roux, Janine Arts
  • Substituted Indolyl-Alkyl-Amino-Derivatives as Inhibitors of Histone Deacetylase
    Publication number: 20090018153
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 16, 2007
    Publication date: January 15, 2009
    Inventors: Patrick Rene Angibaud, Isabelle Noelle Constance Pilatte
  • Sulfonyl-Derivatives as novel inhibitors of histone deacetylase
    Patent number: 7205304
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: April 17, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Kristof Van Emelen, Janine Arts, Leo Jacobus Jozef Backx, Hans Louis Jos De Winter, Sven Franciscus Anna Van Brandt, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Isabelle Noëlle Constance Pilatte, Virginie Sophie Poncelet, Alexey Borisovich Dyatkin, Jimmy Arnold Viviane Van heusden
  • Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors
    Patent number: 7053105
    Abstract: This invention comprises the novel compounds of formula (I) wherein r, s, t, Y1—Y2, R1, R2, R3, R4, R5 and R7 have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: May 30, 2006
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Patrick René Angibaud, Marc Gaston Venet, Isabelle Noëlle Constance Pilatte
  • Triazolobenzazepine derivatives
    Patent number: 5932569
    Abstract: Antiallergic triazolobenzazepines of formula ##STR1## wherein each of the dotted lines independently represents an optional bond; R.sup.1 represents hydrogen, halo, C.sub.1-4 alkyl, hydroxy or C.sub.1-4 alkyloxy; R.sup.2 represents hydrogen, halo, C.sub.1-4 alkyl, hydroxy or C.sub.1-4 alkyloxy; R.sup.3 represents hydrogen, C.sub.1-4 alkyl or halo; --B.dbd.D-- is a bivalent radical of formula --C(R.sup.4).dbd.N--(a-1); or --N.dbd.C(R.sup.5)-- (a-2); R.sup.4 and R.sup.5 represent hydrogen, C.sub.1-4 alkyl, ethenyl substituted with hydroxycarbonyl or C.sub.1-4 alkyloxycarbonyl, C.sub.1-4 alkyl substituted with hydroxycarbonyl or C.sub.1-4 alkyloxycarbonyl, hydroxyC.sub.1-4 alkyl, formyl or hydroxycarbonyl; R.sup.5 also represents phenyl or pyridinyl; L represents hydrogen; C.sub.1-6 alkyl; substituted C.sub.1-6 alkyl, C.sub.3-6 alkenyl; C.sub.3-6 alkenyl substituted with aryl or, L represents a radical of formula -Alk-Y-Het.sup.1 (b-1), -Alk-NH--CO--Het.sup.2 (b-2) or --Alk-Het.sup.3 (b-3).
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: August 3, 1999
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Frans Eduard Janssens, Jean Fernand Armand Lacrampe, Isabelle Noelle Constance Pilatte