Patents by Inventor Isabelle Roland

Isabelle Roland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasma membrane biomarkers preferentially expressed in pancreatic beta cells useful in imaging or targeting beta cells
    Patent number: 8425878
    Abstract: The present invention is directed to the identification of a biomarker specifically located in the plasma membrane of pancreatic beta cells. It was selected by a Systems Biology approach on Massively Parallel Signal Sequencing datasets obtained in human islets and Affymetrix microarray datasets on human islets, purified rat primary beta and non beta cells and insulinoma cells. Based on a set of specific features the biomarker is a unique candidate for imaging and targeting strategies to study the pancreatic beta cell mass in health and disease (T1 D, T2D, pancreatic cancers, obesity, islet transplantation, beta cell regeneration).
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: April 23, 2013
    Assignee: Universite Libre de Bruxelles
    Inventors: Decio L. Eizirik, Daisy Flamez, Isabelle Salmon, Alix Berton, Isabelle Roland, Daniel Marechal, Marie-Claire Beckers, Leroy Hood, Nathan Goodman, Burak Kutlu
  • NEW PLASMA MEMBRANE BIOMARKERS PREFERENTIALLY EXPRESSED IN PANCREATIC BETA CELLS USEFUL IN IMAGING OR TARGETING BETA CELLS
    Publication number: 20100322850
    Abstract: The present invention is directed to the identification of a biomarker specifically located in the plasma membrane of pancreatic beta cells. It was selected by a Systems Biology approach on Massively Parallel Signal Sequencing datasets obtained in human islets and Affymetrix microarray datasets on human islets, purified rat primary beta and non beta cells and insulinoma cells. Based on a set of specific features the biomarker is a unique candidate for imaging and targeting strategies to study the pancreatic beta cell mass in health and disease (T1 D, T2D, pancreatic cancers, obesity, islet transplantation, beta cell regeneration).
    Type: Application
    Filed: February 13, 2009
    Publication date: December 23, 2010
    Inventors: Decio L. Eizirik, Daisy Flamez, Isabelle Salmon, Alix Berton, Isabelle Roland, Daniel Marechal, Marie-Claire Beckers, Leroy Hood, Nathan Goodman, Burak Kutlu