Abstract: A genomic test processing system and method employ an order management engine and one or more order processing engines, the order processing engines including a receiving engine, an execution engine, and a broadcasting engine. The receiving engine receives a state of an order from the order management engine. The execution engine determines a sequence of steps to advance the received state of an order to a final state, iteratively designates each step of the sequence of steps as completed before initiating the next step of the sequence of steps, and advances the state of the order to a final state when a last step of the sequence of steps is completed. The broadcasting engine broadcasts the final state of the order to the order management engine. The order management engine causes one of the order processing engines to generate a next-generation sequencing report from the final state of the order.