Abstract: Technologies for securely processing payment transactions include a mobile device configured to generate a secure payment transaction request message for a payment transaction. The request message includes a public key address derived from a public key of a public/private key pair. A multi-factor device receives the request message and generates a reference public key address as a function of the corresponding private key of the public/private key pair. The multi-factor device determines whether the public key address included in the received request message matches the generated reference public key address. The multi-factor device generates and transmits a response message to the mobile device including status indicator data based on the determination whether the received public key address matches the generated reference public key address. The mobile device processes or blocks the payment transaction as a function of the status indictor data. Other embodiments are described and claimed.

Abstract: The present disclosure is directed to fulvestrant at a dosage of 500 mg and its use in the treatment of a postmenopausal woman with advanced breast cancer.