Patents by Inventor Isamu Itoh
Isamu Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8471036Abstract: A rhodacyanine derivative represented by the following General Formula (1), wherein, in General Formula (1), R1, R2, and R3 each independently represent an alkyl group which may be substituted; Y1 and Y2 each independently represent a hydrogen atom, a chlorine atom, or a fluorine atom provided that Y1 and Y2 do not represent hydrogen atoms at the same time; and X represents a counter anion. A pharmaceutical composition for treating leishmaniasis including the rhodacyanine derivative and a pharmaceutically acceptable carrier.Type: GrantFiled: October 6, 2010Date of Patent: June 25, 2013Assignees: FUJIFILM Corporation, Hoshi UniversityInventors: Masataka Ihara, Isamu Itoh
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Patent number: 8288374Abstract: Provided is a medicinal composition, in particular, a medicinal composition for treatment and/or prevention which has a high therapeutic effect on infection with a parasitic protozoa and a selective toxicity thereto and exhibits a life-prolonging effect and so on. A medicinal composition which contains as the active ingredient a benzo[a]phenoxazine compound represented by General formula (1) or a salt compound of the same, in particular, an agent for treating and/or preventing infection with a protozoa such as malaria, leishmaniasis, African trypanosomiasis, Chagas disease, toxoplasmosis, lymphatic filariasis, babesiosis or coccidium disease; and a novel compound which is contained therein as the active ingredient.Type: GrantFiled: March 11, 2009Date of Patent: October 16, 2012Assignees: Hoshi University, Synstar Japan Co., Ltd., Swiss Tropical and Public Health Institute, FUJIFILM CorporationInventors: Masataka Ihara, Jian-Feng Ge, Chika Arai, Nasser Saad Mohamed Ismail, Mei Yang, Isamu Itoh, Reto Brun
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Publication number: 20120220639Abstract: A rhodacyanine derivative represented by the following General Formula (1), wherein, in General Formula (1), R1, R2, and R3 each independently represent an alkyl group which may be substituted; Y1 and Y2 each independently represent a hydrogen atom, a chlorine atom, or a fluorine atom provided that Y1 and Y2 do not represent hydrogen atoms at the same time; and X represents a counter anion. A pharmaceutical composition for treating leishmaniasis including the rhodacyanine derivative and a pharmaceutically acceptable carrier.Type: ApplicationFiled: October 6, 2010Publication date: August 30, 2012Applicants: HOSHI UNIVERSITY, FUJIFILM CORPORATIONInventors: Masataka Ihara, Isamu Itoh
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Publication number: 20110021450Abstract: Provided is a medicinal composition, in particular, a medicinal composition for treatment and/or prevention which has a high therapeutic effect on infection with a parasitic protozoa and a selective toxicity thereto and exhibits a life-prolonging effect and so on. A medicinal composition which contains as the active ingredient a benzo[a]phenoxazine compound represented by General formula (1) or a salt compound of the same, in particular, an agent for treating and/or preventing infection with a protozoa such as malaria, leishmaniasis, African trypanosomiasis, Chagas disease, toxoplasmosis, lymphatic filariasis, babesiosis or coccidium disease; and a novel compound which is contained therein as the active ingredient.Type: ApplicationFiled: March 11, 2009Publication date: January 27, 2011Applicants: HOSHI UNIVERSITY, SYNSTAR JAPAN CO., LTD., SWISS TROPICAL AND PUBLIC HEALTH INSTITUTEInventors: Masataka Ihara, Jian-Feng Ge, Chika Arai, Mei Yang, Isamu Itoh, Reto Brun
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Patent number: 7161022Abstract: A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting a sulfuric ester, an aromatic hydrocarbon and a maleic anhydride derivative.Type: GrantFiled: May 14, 2003Date of Patent: January 9, 2007Assignees: Fujifilm Finechemicals Co., Ltd., Meiji Seika Kaisha, Ltd.Inventors: Isamu Itoh, Taichi Shintou
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Publication number: 20050176994Abstract: A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting a sulfuric ester, an aromatic hydrocarbon and a maleic anhydride derivative.Type: ApplicationFiled: May 14, 2003Publication date: August 11, 2005Applicants: SANKIO CHEMICAL CO., LTD., MEIJI SEIKA KAISHA, LTD.Inventors: Isamu Itoh, Taichi Shintou
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Patent number: 5612840Abstract: A magnetic head unit is provided by which damage to a conductive-pattern layer formed on a spring arm during a bending process of the spring arm can be prevented. The magnetic head unit comprises a magnetic head and a spring arm having a bent portion which is bent to generate an elastic force. The magnetic head is mounted on an end of the spring arm. At least one conductive-pattern layer is formed on a surface of the spring arm to extend from a gimbal portion where the magnetic head is mounted to a attachment portion where the spring arm is mounted to a member of a magnetic head driving mechanism. The bent portion has a first portion and a second portion separated from the first portion. The conductive-pattern layer passes through the second portion. No external force is applied to the conductive-pattern layer formed during a bending process for the bent portion.Type: GrantFiled: May 24, 1994Date of Patent: March 18, 1997Assignee: Fujitsu LimitedInventors: Sinji Hiraoka, Yoshihisa Matsumoto, Isamu Itoh, Shigeo Terashima
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Patent number: 5180652Abstract: A light- and heat-sensitive composition which contains a photo-hardenable composition and at least one dye, a light- and heat-sensitive recording material which contains a support having the composition provided on at least one side thereof, and an image-forming process using the recording material are disclosed.Type: GrantFiled: January 18, 1990Date of Patent: January 19, 1993Assignee: Fuji Photo Film Co., Ltd.Inventors: Jun Yamaguchi, Sadao Ishige, Kozo Sato, Shintaro Washizu, Isamu Itoh
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Patent number: 4910128Abstract: A silver halide color photographic material comprising as a cyan-dye-forming coupler a compound represented by of formula (I) ##STR1## wherein R.sub.1 represents a ballast group imparting diffusion fastness to the coupler of formula (I) and a cyan dye formed from said coupler; X represents a hydrogen atom or a group represented by --R, --OR, --SR, ##STR2## --COR, --COOR, --SO.sub.2 R, --SO.sub.2 OR, ##STR3## or --OCOR; Y represents a halogen atom, a cyano group, a trifluoromethyl group, a nitro group, or a group represented by --R, --OR, --SR, --COR, --COOR, --SO.sub.2 R, --SO.sub.2 OR, ##STR4## m and n each represents an integer of 1 to 5, and when m or n is more than 1, the X or Y, respectively, are the same or different; R represents an aliphatic group, an aromatic group, or a heterocyclic group, and R' and R" each represents a hydrogen atom, an aliphatic group, an aromatic group, or a heterocyclic group; with the proviso that the total number of carbon atoms in the substituent (X).sub.m is 4 or more.Type: GrantFiled: September 19, 1988Date of Patent: March 20, 1990Assignee: Fuji Photo Film Co., Ltd.Inventors: Takayoshi Kamio, Katsuyoshi Yamakawa, Hidetoshi Kobayashi, Isamu Itoh
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Patent number: 4888268Abstract: A silver halide photographic material, which contains at least one blocked photographic reagent having in the molecule thereof at least one group selected from ##STR1## group and capable of releasing a photographically useful reagent by cleavage of the --N--C--bond by a nucleophilic attack of a nucleophilic reagent on the carbonyl group and a subsequent intramolecular electron transfer reaction or intramolecular nucleophilic reaction and which has at least one photosensitive silver halide emulsion layer, is photographically processed in the presence of an amine. A photographic material which includes, in combination, a photographic reagent precursor capable of releasing a photographically useful reagent timely on photographic processing and a photosensitive silver halide emulsion layer is provided along with a method of processing the photographic material.Type: GrantFiled: August 16, 1988Date of Patent: December 19, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Isamu Itoh, Mitsunori Ono, Yoshio Inagaki
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Patent number: 4845020Abstract: A method of processing a silver halide photographic material comprising processing the silver halide photographic material in the presence of an antifoggant which is an organic compound which loses its developing restraining function by a reduction oxidation reaction with oxidized developers. The method improves the discrimination between image and non-image areas of the silver halide photographic material by the novel antifoggant which restrains fog selectively in non-image areas without decreasing photographic sensitivity and image density. The organic compound can be an anti-foggant which possesses a moiety according to the Kendall-Pelz rule and either a mercapto group or a cyclic NH group.Type: GrantFiled: July 24, 1987Date of Patent: July 4, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Isamu Itoh, Keiji Mihayashi
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Patent number: 4842985Abstract: A conventional silver halide color photographic material is described, containing a coupler having a dye moiety having the maximum absorption wave length shifted to a short wave length by a linkage which is cleaved directly or through a timing group by a coupling reaction with the oxidation product of a developing agent and forming a compound or the precursor thereof (compound A) having a dye moiety having the maximum absorption wave length before shifting as the result of the above-described reaction and a compound capable of fixing the hue of the compound A at a long wave length and/or capable of immobilizing the compound A in the photographic layer.Type: GrantFiled: December 8, 1987Date of Patent: June 27, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Mitsunori Ono, Koji Tamoto, Keiji Mihayashi, Seiji Ichijima, Isamu Itoh, Yoshisada Nakamura
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Patent number: 4831152Abstract: Novel benzoxazole compound having, at the 2 position, a group bonding through a carbon atom having no or one hydrogen atom and introduced with a chlorine or bromine atom at the 5 position. The compounds are key intermediates useful for preparing 2-amino-5-nitrophenol derivatives which are useful as intermediates for synthesis of industrial materials, reducing agents, antioxidants, cyan-image-forming couplers and the like.Type: GrantFiled: June 14, 1985Date of Patent: May 16, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Isamu Itoh, Mitsunori Ono, Hidetoshi Kobayashi, Kazuyoshi Yamakawa
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Patent number: 4772537Abstract: A silver halide photographic material which contains at least one blocked photographic reagent having in the molecule thereof at least one ##STR1## structure and capable of releasing a photogrpahically useful reagent by cleavage of the ##STR2## bond by a nucleophilic attack of a nucleophilic reagent on the structure and a subsequent intramolecular electron transfer reaction or an intramolecular nucleophilic reaction and which has at least one photosensitive silver halide emulsion layer. There is provided a photogrphic material which includes, in combination, a photographic reagent precursor capable of releasing a photographically useful reagent timely on photographic processing and a photosensitive silver halide emulsion layer.Type: GrantFiled: September 18, 1986Date of Patent: September 20, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Isamu Itoh, Mitsunori Ono
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Patent number: 4743595Abstract: A process for efficiently preparing 2-amino-5-nitrophenol derivatives in which benzoxazole derivatives are subjected to nucleophilic substitution reaction at the 5 position thereof to obtain corresponding benzoxazole derivatives, and the oxazole ring of the benzoxazole derivatives is then subjected to ring-opening to obtain 2-amino-5-nitrophenol derivatives. The 2-amino-5-nitrophenol derivatives are useful as industrial starting materials, reducing agents or antioxidants and intermediates for cyan-image-forming couplers.Type: GrantFiled: June 12, 1985Date of Patent: May 10, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Isamu Itoh, Mitsunori Ono, Hidetoshi Kobayashi, Kazuyoshi Yamakawa
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Patent number: 4740453Abstract: A silver halide photosensitive material is described, comprising a support and at least one silver halide emulsion layer, wherein said emulsion layer or another layer contains a compound represented by formula (I) ##STR1## wherein X represents an atomic group forming a redox center of benzene type having substituents by linking with C.sub.A and C.sub.B, and which does not enable Time-PUG to be released until the redox center is oxidized during development processing; EWG represents an electron withdrawing group having a Hammet's .sigma. para value exceeding 0.3; C.sub.A and C.sub.B each represents a carbon atom; R.sub.1 and R.sub.2 each represents a hydrogen atom or a suitable substituent; Time represents a timing group connecting to C.sub.B through a sulfur, nitrogen, or selenium atom thereof, t is an integer of 0 or 1, and when t=0, Time is a chemical bond; PUG represents a photographically useful group and connects to C.sub.Type: GrantFiled: December 24, 1985Date of Patent: April 26, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Koki Nakamura, Shigeo Hirano, Tadashi Ikeda, Keiji Mihayashi, Mitsunori Ono, Toshiro Takahashi, Ken-ichi Kuwabara, Morio Yagihara, Isamu Itoh
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Patent number: 4734353Abstract: A method for processing a silver halide photographic light-sensitive material comprising a support having thereon a light-sensitive silver halide emulsion layer having associated therewith a blocked photographic agent capable of releasing a photographically useful agent, which method comprises processing the photographic light-sensitive material in the presence of an oxime.According to this method for processing a silver halide photographic light-sensitive material, both stability of the photographic light-sensitive material during storage and release of a photographically useful agent during processing are achieved without undersirable side-reactions, and a high sensitivity/fog ratio is obtained.Type: GrantFiled: April 21, 1986Date of Patent: March 29, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Mitsunori Ono, Isamu Itoh, Keiji Mihayashi
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Patent number: 4734357Abstract: A silver halide color light-sensitive material is described, which is increased in sensitivity, is adapted to form an image of high contrast, or is accelerated in development by incorporating a small amount of a specific compound which imagewise releases a foggant or a development accelerator. This compound is represented by the formula: Coup-(TIME).sub.n -FA (wherein Coup represents a coupler radical capable of undergoing a coupling reaction with an oxidized product of an aromatic primary amine developing agent; TIME represents a timing group which is eliminated from Coup by the coupling reaction and, thereafter, releases FA; n is 0 or 1; and FA represents a group which is eliminated from Coup in the coupling reaction when n is 0, whereas FA is released from TIME when n is 1. The FA has adsorption properties with respect to silver halide grains and also has a substantial fogging action with respect to the silver halide grains).Type: GrantFiled: January 14, 1987Date of Patent: March 29, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Keiji Mihayashi, Hidetoshi Kobayashi, Isamu Itoh
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Patent number: 4724199Abstract: A silver halide photographic light-sensitive material containing, in at least one layer thereof, a compound capable of releasing a fogging agent upon an oxidation-reduction reaction with an oxidation product of a developing agent under an alkaline condition. The material has an increased sensitivity, an increased contrast and an accelerated development rate.Type: GrantFiled: October 28, 1985Date of Patent: February 9, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Hidetoshi Kobayashi, Masaharu Toriuchi, Isamu Itoh
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Patent number: 4711837Abstract: A silver halide color photographic material comprising a support having provided thereon at least one silver halide emulsion layer, wherein the photographic material contains a compound having a dye portion in which the maximum absorption wavelength is shifted by a bond that is cleaved upon reaction with an oxidation product of a developing agent and is capable of forming a diffusion resistant compound having a dye portion possessing the maximum absorption wavelength which is not shifted as a result of the reaction with an oxidation product of a developing agent.By the use of the compound which permits a large degree of freedom with respect to selection of the dye for forming a color image according to the present invention, the color photographic material has an excellent image quality, and a good fastness of image or a high sensitivity.Type: GrantFiled: August 27, 1985Date of Patent: December 8, 1987Assignee: Fuji Photo Film Co., Ltd.Inventors: Seiji Ichijima, Mitsunori Ono, Isamu Itoh, Keiji Mihayashi, Koji Tamoto, Yoshisada Nakamura