Patents by Inventor Isamu Saeki

Isamu Saeki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210346301
    Abstract: The main object is to provide a novel pharmaceutical solid preparation containing a pharmaceutically active ingredient, wherein the solid preparation is coated with a light shielding agent in a nano-order thickness. The present invention can include a pharmaceutical solid preparation containing at least one pharmaceutically active ingredient, wherein the surface of the solid preparation is coated with a light shielding agent or a metal oxide to a thickness in a range of 1 nm to 500 nm to form a coating layer, or is coated with a light shielding agent or a metal oxide which is present in a range of 5×10?6 mg/mm2 to 3×10?3 mg/mm2 to form a coating layer, and a process for producing a solid preparation containing at least one pharmaceutically active ingredient, comprising a step of coating a light shielding agent or a metal oxide by sputtering on the surface of the solid preparation to a thickness in a range of 1 nm to 500 nm.
    Type: Application
    Filed: October 16, 2019
    Publication date: November 11, 2021
    Applicant: Towa Pharmaceutical Co., Ltd.
    Inventors: Yutaka Okuda, Isamu Saeki, Tatsuya Honjo, Kayo Yuminoki
  • Publication number: 20210196635
    Abstract: The present invention provides a method of efficiently manufacturing drug-containing particle which has a sharp peak in the particle size distribution, is highly spherical, and good in fluidity. The present invention relates to a manufacturing method of a drug-containing particle, the drug-containing particle comprising a raw material particle and a coating layer on the outside of the raw material particle, the raw material particle and/or the coating layer comprising at least one drug, wherein the manufacturing method comprises a granulation process that agitates a mixture comprising a core particle for powder coating formed by coating the raw material particle with a polymer and a drug and/or pharmaceutically acceptable additive while spraying a solvent which can dissolve the polymer on the mixture.
    Type: Application
    Filed: August 27, 2019
    Publication date: July 1, 2021
    Inventors: Yutaka Okuda, Isamu Saeki, Tatsuya Honjo, Keisuke Hiraishi, Kayo Yuminoki
  • Publication number: 20210059948
    Abstract: An orally disintegrating tablet combinable with a variety of drugs and exhibits excellent disintegrating properties in an oral cavity but having strength and the like allowing ability to form a tablet. The annular orally disintegrating tablet containing a drug and a disintegrating agent; and having a hole in a central portion making it annular. The content of the disintegrating agent relative to total weight is 2% to 50% by weight. It exhibits excellent disintegrating properties, i.e., when a gradient of disintegrating time (seconds) of the tablet with respect to tableting pressure (kN) upon compression-forming is defined as “a” and a gradient of disintegrating time (seconds) of a disk-shaped orally disintegrating tablet with respect to tableting pressure (kN) upon compression-forming is defined as “b”, the disk-shaped orally disintegrating tablet having the same weight and external diameter as the annular orally disintegrating tablet the ratio (a/b) is 0.90 or less.
    Type: Application
    Filed: December 26, 2018
    Publication date: March 4, 2021
    Applicant: TOWA PHARMACEUTICAL CO., LTD.
    Inventors: Tatsuya HONJO, Isamu SAEKI, Yutaka OKUDA
  • Publication number: 20190328674
    Abstract: Disclosed are orally disintegrating tablet having advantageous physical strength and disintegrability, and their method for production. The orally disintegrating tablet is a compression molding product of a mixture comprising granules A that contains a pharmaceutically active ingredient, and at least a disintegrant, wherein (a) the mean particle size of granules A is not greater than 300 ?m, (b) the particle distribution index for granules A is 3.0 or less, and (c) the angle of repose of granules A is not greater than 38 degrees.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 31, 2019
    Inventors: Isamu SAEKI, Yuki MATSUSHIMA, Hiroko KABASHIMA, Yutaka OKUDA
  • Patent number: 8409594
    Abstract: The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological functions of an electrolyte. A solid composition is obtained by preparing an oil-in-water emulsion by combining a solid oil (A), a liquid oil (B), a surfactant (C), a polyhydric alcohol (D), an electrolyte (E), and water (F).
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: April 2, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Shigeo Shinohara, Fumiki Harano, Shinji Tsujimoto, Isamu Saeki
  • Publication number: 20070280979
    Abstract: The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological functions of an electrolyte. A solid composition is obtained by preparing an oil-in-water emulsion by combining a solid oil (A), a liquid oil (B), a surfactant (C), a polyhydric alcohol (D), an electrolyte (E), and water (F).
    Type: Application
    Filed: December 12, 2005
    Publication date: December 6, 2007
    Inventors: Shigeo Shinohara, Fumiki Harano, Shinji Tsujimoto, Isamu Saeki