Patents by Inventor Isamu Watanabe

Isamu Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4353893
    Abstract: A compound of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are different and each represents a hydrogen atom or a methyl group, R.sub.3 represents a hydrogen atom, or a glycyl group which may be substituted, and the symbol between the carbon atoms at the 5- and 6- positions represents a single or double bond, and an acid addition salt thereof; and its antibiotic use.
    Type: Grant
    Filed: May 20, 1981
    Date of Patent: October 12, 1982
    Assignee: Kowa Company, Ltd.
    Inventors: Isamu Watanabe, Takashi Yamaguchi, Kazuhiro Kamiya, Toshihito Mori
  • Patent number: 4255421
    Abstract: Novel aminoglycosides of the following formula ##STR1## wherein R.sub.1 and R.sub.2 are identical or different and each represents a hydrogen atom or a methyl group, R.sub.3 represents a hydrogen atom or an optionally substituted aminoacyl group having 2 to 4 carbon atoms in the acyl moiety, and when all of R.sub.1, R.sub.2 and R.sub.3 are hydrogen atoms, the methylamino group at the 4-position is not oriented trans to the hydroxyl groups at the 3- and 5-positions; and acid addition salts thereof, which are useful as antibiotics; and process for producing compounds containing the same.
    Type: Grant
    Filed: October 12, 1979
    Date of Patent: March 10, 1981
    Assignee: Kowa Company, Ltd.
    Inventors: Isamu Watanabe, Akio Iwasaki, Toshihito Mori
  • Patent number: 4065616
    Abstract: This invention relates to new processes for the production of a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-3'-deoxy-5-O-pentofuranosylnea mine, including 3'-deoxybutirosins A and B, as a semi-synthetic antibiotic. This invention further relates to new and useful semi-synthetic antibiotics which are produced by the above new processes.
    Type: Grant
    Filed: August 2, 1976
    Date of Patent: December 27, 1977
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Sumio Umezawa, Tsutomu Tsuchiya, Isamu Watanabe
  • Patent number: 3956274
    Abstract: Lividomycin B derivatives having enhanced antibacterial activity are provided; the 6'-deoxy-6' substituted or unsubstituted amino lividomycins are prepared by masking the functional groups other than the 4' - and 6' -hydroxyl groups, converting the 6' hydroxyl group to an amino group and then removing the remaining protective groups.
    Type: Grant
    Filed: March 5, 1974
    Date of Patent: May 11, 1976
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Sumio Umezawa, Hamao Umezawa, Osamu Tsuchiya, Isamu Watanabe