Patents by Inventor Isao Ishimaru

Isao Ishimaru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA ACTION INHIBITOR AND USE THEREOF
    Publication number: 20220401466
    Abstract: An agent for inhibiting the action of a target RNA based on RNA interference and ASO with a passenger strand and a guide strand for a target RNA, wherein both ends of double-stranded RNA formed pairing of the passenger strand and the guide strand are blunt ends, and one or two or more selected from the group consisting of the units represented by formula (1) and formula (2) below at the following positions (a) and (b): (a) 5? end side and 3? end side of the passenger strand, (b) 3? end side of the guide strand (in which X represents an oxygen atom or sulfur atom), (in which X represents an oxygen atom or sulfur atom).
    Type: Application
    Filed: August 20, 2020
    Publication date: December 22, 2022
    Applicants: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, NICCA CHEMICAL CO., LTD., HOKKAIDO SYSTEM SCIENCE CO., LTD.
    Inventors: Hiroyuki ASANUMA, Yukiko KATO, Keiji MURAYAMA, Toshiki TSUBOI, Tomohito DOKE, Takuji ISHIMOTO, Shoichi MARUYAMA, Toshio KOKURYO, Ayako KOTO, Isao ISHIMARU, Ryoichi ASAI, Ayaka NAKASHA, Tomoe SUGITA, Keisuke NISHI, Motoki YUGUCHI, Masanori MATSUMOTO
  • Photoresponsive nucleotide analog capable of photocrosslinking in visible light region
    Patent number: 11078211
    Abstract: Provided are a compound represented by the following formula I; a novel photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking agent in which the photoreactive compound is used.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: August 3, 2021
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, NICCA CHEMICAL CO., LTD.
    Inventors: Takahiro Inatsugi, Ayako Koto, Isao Ishimaru, Masahiko Takamura, Kenzo Fujimoto
  • PHOTORESPONSIVE NUCLEOTIDE ANALOG CAPABLE OF PHOTOCROSSLINKING IN VISIBLE LIGHT REGION
    Publication number: 20200317685
    Abstract: Provided are a compound represented by the following formula I; a novel photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking agent in which the photoreactive compound is used.
    Type: Application
    Filed: July 19, 2018
    Publication date: October 8, 2020
    Applicants: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, NICCA CHEMICAL CO., LTD.
    Inventors: Takahiro Inatsugi, Ayako Koto, Isao Ishimaru, Masahiko Takamura, Kenzo Fujimoto