Patents by Inventor Isidro Ferrer Abizanda

Isidro Ferrer Abizanda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100285483
    Abstract: The invention describes methods of molecular diagnosis of a concrete form of ?-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 11, 2010
    Applicant: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Publication number: 20100247543
    Abstract: The treatment and prevention of neurodegenerative diseases by repression of the transcriptional complex that silences the promoter of the UCHL1 gene.
    Type: Application
    Filed: February 24, 2010
    Publication date: September 30, 2010
    Applicant: ORYZON GENOMICS, S.A.
    Inventors: Tamara Maes, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Patent number: 7745127
    Abstract: The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: June 29, 2010
    Assignee: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Publication number: 20090028845
    Abstract: The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Application
    Filed: July 18, 2005
    Publication date: January 29, 2009
    Applicant: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Publication number: 20080318221
    Abstract: The present invention relates to a method for the diagnosis and/or prognosis of Alzheimer's disease by means of determining the DARC gene expression level in a biological sample and comparing said level with a reference value, in which the disturbance of said level is indicative of Alzheimer's disease.
    Type: Application
    Filed: June 20, 2007
    Publication date: December 25, 2008
    Applicants: FINA BIOTECH, S.L., ORYZON GENOMICS, S.A.
    Inventors: Elisabet Rosell Vives, Marta Barrachina Castillo, Isidro Ferrer Abizanda, Tamara Maes
  • Publication number: 20080318220
    Abstract: The present invention relates to a method for the diagnosis and/or prognosis of Alzheimer's disease by means of determining the ZMIZ1 gene expression level in a biological sample and comparing said level with a reference value, in which the alteration of said level is indicative of Alzheimer's disease.
    Type: Application
    Filed: June 20, 2007
    Publication date: December 25, 2008
    Applicants: FINA BIOTECH, S.L., ORYZON GENOMICS, S.A.
    Inventors: Elisabet Rosell Vives, Marta Barrachina Castillo, Isidro Ferrer Abizanda, Tamara Maes
  • Publication number: 20080206762
    Abstract: The invention relates to a method for the diagnosis and/or prognosis of Alzheimer's disease, consisting in determining the expression level of a gene encoding a lysosomal marker.
    Type: Application
    Filed: May 17, 2006
    Publication date: August 28, 2008
    Applicant: FINA BIOTECH,S.L.U.
    Inventors: Isidro Ferrer Abizanda, Marta Barrachina Castillo, Francisco Subirada Sole, Olga Maria Durany Turk, Carlos Manuel Buesa Arjol, Tamara Maes