Abstract: A transmit sequence for contrast agent imaging that improves sensitivity and minimizes image artifacts. The number of pulses and the interleaving of spatially distinct pulses between spatially co-linear pulses are selected such that a substantially similar pulse sequence for substantially each line in a scanned region is generated. A collateral pulse from a different scan line is interleaved between at least two imaging pulses along a scan line of interest. Such pulse sequences provide sensitive contrast agent imaging with minimized spatial variation. In another aspect, responsive signals representing the first and second scan lines are obtained. Intensities associated with the signals are determined. The intensities associated with the first scan line are compared to a value.

Abstract: Minimum arc interpolation is performed on velocity information distributed in three dimensions. By using complex representations of the velocity information, the interpolation may more accurately represent the angle or velocity for spatial conversion. Tri-linearly interpolating velocity information converts the information representing a three-dimensional volume to a reconstruction grid. The interpolation is performed with a graphics processing unit. Complex representations of the velocity are loaded as texture data. The graphics processing unit interpolates the data as texture fields. Look-up tables are used to determine an angle from the interpolated complex representation and/or a color value for displaying velocities associated with different spatial locations.

Abstract: An intelligent ultrasound examination storage system is disclosed, which permits a sonographer to focus entirely on the examination process while the system analyses image data and marks events of interest for post-examination review or storage.

Abstract: The same analytic data is combined in response to different relative phases. The resulting combinations are detected. The combination associated with the maximum magnitude is then selected for further processing. As a result, the complex data is processed across a variety of possible temporal discontinuities using candidate or possible phase shifts. The phase shift with the least cancellation and the associated combination is selected to minimize motion artifact cancellation.

Abstract: A volumetric method for 2-D flow imaging is provided in medical diagnostic ultrasound. Flow data for a volume is acquired. For more rapid acquisition, broad beam transmission and reception along many scan lines distributed in the volume is used. The volumetric flow data is filtered, such as by calculating statistical information, to generate a planar/2-D flow image. The statistical information from the three-dimensional flow data is used to determine the display values for the flow imaging.

Abstract: Data is captured for different contrast agent perfusion imaging options. For example, two different maximum intensity projection (MIP) combinations of frames are formed during scanning, one with motion correction and one without. As another example, the component frames of data are stored to allow any combination after scanning. If one combination is less desirable, then another combination may be provided without requiring further injection or additional scanning. In another embodiment, the sufficiency of combination is detected and the combination of frames is selected automatically as a function of ultrasound data.

Abstract: Contrast agent enhanced medical diagnostic imaging is provided. Frames of data from common phase periods are grouped. Motion correction is performed within each common phase group. An image representing contrast agents is formed from a combination of the frames within each common phase, motion corrected group.

Abstract: The effectiveness of contrast agent destruction is determined. Locations of ineffectively destroyed contrast agents are identified. The response from undestroyed contrast agents may be distinguished from response from tissue due to saturation or from rapid perfusion. The locations may be highlighted on resulting images, indicating to the user locations not associated with perfusion. The user may make a diagnosis on perfusion rather than a lack of destruction of contrast agents.

Abstract: Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence.

Abstract: Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence.

Abstract: Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence.

Abstract: Clinical markers are adaptively identified in steered spatial compounding ultrasound imaging. Motion is detected. The use or determination of the clinical marker information adapts to the amount of motion. If sufficient motion is detected, the contribution of clinical marker information may be reduced, the weighting of the clinical marker information relative to the steered compound information is reduced, the acquisition sequence is adjusted for component frames of data, or combinations thereof.

Abstract: Contrast agent enhanced medical diagnostic imaging is improved by selecting particular frames of data. Frames of data are acquired over time. Information from the frames of data are combined, such as for a time intensity curve or maximum intensity processing. Rather than combining information from each of the frames, information from some frames is not used. Frames are selected for inclusion. In one embodiment, the selection is based on one type of data (e.g., B-mode) for combining information for another type of data (e.g., contrast agent data).

Abstract: Control of the sonothrombolysis treatment is automated based on feedback from ultrasound. The region to be treated may be tracked to provide ongoing treatment at the desired location. The treatment may be triggered based on detection of sufficient perfusion. The number or intensity of destructive ultrasound pulses may adapt to the number of remaining contrast agents. The treatment may be ceased or modified based on the efficacy.

Abstract: Contrast agents may more effectively clear a clot if they are as close to the clot as possible. Radiation force may effectively push and/or pull the contrast agents next to the clot and away from the middle of any flow channels. By transmitting driving acoustic energy, the contrast agents may be positioned for treatment that is more effective by destruction.

Abstract: Destructive or therapy events are indicated in medical ultrasound imaging. Audible, visual, vibratory or other feedback is provided to the user. The feedback indicates the use of the destructive or therapy events. A characteristic of the indicator may provide further information, such as the power level or other operating condition.

Abstract: Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence.

Abstract: Automated determination and setting of an ultrasound system transmit power level is provided for contrast agent imaging. Low mechanical index imaging of contrast agents allows substantially continuous imaging of contrast agents without destruction. By comparing data associated with different transmit power levels, different delays between acquisition or different acquisition sequences, a contrast agent imaging transmit power generally minimizing destruction of contrast agents and maximizing signal-to-noise ratio is automatically determined.

Abstract: Methods and systems are provided for identifying clinical markers in spatial compounded imaging. For example, an image responsive to less spatial compounding more likely preserves clinical markers than a steered compound image. By displaying both images, clinical markers are identified by the user from one image and other diagnostic information is obtained from the steered compound image. As another example, clinical marker information is identified and added back into or highlighted on a spatial compound image for identification by the user.

Abstract: Methods and systems are provided for identifying clinical markers in spatial compounded imaging. For example, an image responsive to less spatial compounding more likely preserves clinical markers than a steered compound image. By displaying both images, clinical markers are identified by the user from one image and other diagnostic information is obtained from the steered compound image. As another example, clinical marker information is identified and added back into or highlighted on a spatial compound image for identification by the user.