Patents by Inventor ISOLDE MARIA FRANCIS

ISOLDE MARIA FRANCIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THAXTOMIN PRODUCTION AND MODIFIED STREPTOMYCES WITH INCREASED THAXTOMIN PRODUCTION
    Publication number: 20190316160
    Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects, relate to genetically modified Streptomyces bacteria capable of increased thaxtomin production, genetically modified Streptomyces bacteria with reduced activity of a CebR protein encoded by a cebR gene and/or reduced activity of a ?-glucosidase enzyme encoded by the bglC gene, genetically modified Streptomyces bacteria including a mutation of a native cebR gene and/or a native bglC gene, methods of increasing thaxtomin production in Streptomyces bacteria, methods of suppressing CebR and/or BglC activity, methods of producing thaxtomin, and thaxtomin produced by the methods of the present disclosure.
    Type: Application
    Filed: May 29, 2019
    Publication date: October 17, 2019
    Inventors: ROSEMARY LORIA, SAMUEL JOURDAN, SEBASTIEN RIGALI, ISOLDE MARIA FRANCIS
  • Methods for thaxtomin production and modified streptomyces with increased thaxtomin production
    Patent number: 10385372
    Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects, relate to genetically modified Streptomyces bacteria capable of increased thaxtomin production, genetically modified Streptomyces bacteria with reduced activity of a CebR protein encoded by a cebR gene and/or reduced activity of a ?-glucosidase enzyme encoded by the bglC gene, genetically modified Streptomyces bacteria including a mutation of a native cebR gene and/or a native bglC gene, methods of increasing thaxtomin production in Streptomyces bacteria, methods of suppressing CebR and/or BglC activity, methods of producing thaxtomin, and thaxtomin produced by the methods of the present disclosure.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: August 20, 2019
    Assignees: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., UNIVERSITE DE LIEGE
    Inventors: Rosemary Loria, Samuel Jourdan, Sebastien Rigali, Isolde Maria Francis
  • METHODS FOR THAXTOMIN PRODUCTION AND MODIFIED STREPTOMYCES WITH INCREASED THAXTOMIN PRODUCTION
    Publication number: 20170306368
    Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects, relate to genetically modified Streptomyces bacteria capable of increased thaxtomin production, genetically modified Streptomyces bacteria with reduced activity of a CebR protein encoded by a cebR gene and/or reduced activity of a ?-glucosidase enzyme encoded by the bglC gene, genetically modified Streptomyces bacteria including a mutation of a native cebR gene and/or a native bglC gene, methods of increasing thaxtomin production in Streptomyces bacteria, methods of suppressing CebR and/or BglC activity, methods of producing thaxtomin, and thaxtomin produced by the methods of the present disclosure.
    Type: Application
    Filed: September 17, 2015
    Publication date: October 26, 2017
    Inventors: ROSEMARY LORIA, SAMUEL JOURDAN, SEBASTIEN RIGALI, ISOLDE MARIA FRANCIS