Abstract: Described herein, are in-wash fabric conditioning compositions, comprising: from about 0.5 to about 40 wt % of an aminopolysiloxane; and water, wherein the aminopolysiloxane and water are present in the form of an emulsion. In-wash fabric conditioning compositions comprising an emulsion comprising from about 0.1 to about 5 wt % of an aminopolysiloxane, based upon the total weight of the in-wash fabric conditioning composition, wherein the aminopolysiloxane comprises amino substituted alkyl moieties, an effective amount of a solvent, and a synthetic wax, are also disclosed. Methods of making and using these compositions are also described.

Abstract: Embodiments and examples are disclosed for intelligent vehicle diagnostics using driving behavior modeling and monitoring. For one example, a data processing system for a vehicle includes a plurality of sensors and a vehicle control unit (VCU). The VCU may sample the output from each of the plurality of sensors and assemble a dataset which may be transmitted to a cloud computing center. The cloud computing center may apply statistical machine learning algorithms to the dataset and training data to develop a model of a user's expected driving behavior. The cloud computing center may transmit the model to the vehicle, wherein the VCU may utilize the model to monitor the user's driving behavior. In response to detecting driving behavior that is anomalous to the expected driving behavior, the VCU may diagnose the cause of the anomalous behavior and take one or more preventative actions based on the diagnosis.

Abstract: A knitted quilt fabric is made of a first layer of a first knit material and a second layer of a second knit material, with a filler material composed of a plurality of plaited lay-in fibers between the two layers. The first layer and second layer are joined at a plurality of locations with knits forming at least one linear quilt line. Each knit of the linear quilt line is formed around a plaited lay-in fiber by knitting a first fiber of the first material to the second material and returning to the first material and knitting a second fiber of the second material to the first material and returning to the second material. Each lay-in fiber is an elastic polyether-polyurea copolymer which is plaited with one or more natural or synthetic yarns.

Abstract: The invention is directed to the treatment of tauopathic neurodegenerative conditions and the underlying processes thereof. Based on the discovery that Rhes acts as a negative regulator of normal tau clearance, the compositions and methods of the invention may be applied to inhibit Rhes and reduce pathogenic tau aggregation. Rhes may be disrupted by disrupting RAS2D gene expression or reducing the abundance of Rhes protein in neurons. Additionally, post-translational modifications of Rhes may be targeted, including the disruption of Rhes farnesylation by the administration of farnesyltransferase inhibitors.

Abstract: The invention is directed to the treatment of tauopathic neurodegenerative conditions and the underlying processes thereof. Based on the discovery that Rhes acts as a negative regulator of normal tau clearance, the compositions and methods of the invention may be applied to inhibit Rhes and reduce pathogenic tau aggregation. Rhes may be disrupted by disrupting RAS2D gene expression or reducing the abundance of Rhes protein in neurons. Additionally, post-translational modifications of Rhes may be targeted, including the disruption of Rhes farnesylation by the administration of farnesyltransferase inhibitors.

Abstract: Described herein, are in-wash fabric conditioning compositions, comprising: from about 0.5 to about 40 wt % of an aminopolysiloxane; and water, wherein the aminopolysiloxane and water are present in the form of an emulsion. In-wash fabric conditioning compositions comprising an emulsion comprising from about 0.1 to about 5 wt % of an aminopolysiloxane, based upon the total weight of the in-wash fabric conditioning composition, wherein the aminopolysiloxane comprises amino substituted alkyl moieties, an effective amount of a solvent, and a synthetic wax, are also disclosed. Methods of making and using these compositions are also described.

Abstract: Embodiments and examples are disclosed for intelligent vehicle diagnostics using driving behavior modeling and monitoring. For one example, a data processing system for a vehicle includes a plurality of sensors and a vehicle control unit (VCU). The VCU may sample the output from each of the plurality of sensors and assemble a dataset which may be transmitted to a cloud computing center. The cloud computing center may apply statistical machine learning algorithms to the dataset and training data to develop a model of a user's expected driving behavior. The cloud computing center may transmit the model to the vehicle, wherein the VCU may utilize the model to monitor the user's driving behavior. In response to detecting driving behavior that is anomalous to the expected driving behavior, the VCU may diagnose the cause of the anomalous behavior and take one or more preventative actions based on the diagnosis.

Abstract: Embodiments and examples are disclosed for intelligent detection of vehicle intrusion using command pattern modeling and analysis. For one example, a vehicle control unit (VCU) may monitor, using a model of a user's expected driving behavior, the user's current driving behavior and detect anomalous driving behavior based on the model. The VCU may determine that the anomalous driving behavior does not correspond to one or more commands on a network bus of the vehicle and analyze, using a command pattern model, a pattern among the one or more commands on the network bus. The VCU may then compare, using the command pattern model, the pattern among the one or more commands to a historical command pattern to determine if an intrusion (e.g., by a hacker) is taking place.

Abstract: The invention is directed to the treatment of tauopathic neurodegenerative conditions and the underlying processes thereof. Based on the discovery that Rhes acts as a negative regulator of normal tau clearance, the compositions and methods of the invention may be applied to inhibit Rhes and reduce pathogenic tau aggregation. Rhes may be disrupted by disrupting RAS2D gene expression or reducing the abundance of Rhes protein in neurons. Additionally, post-translational modifications of Rhes may be targeted, including the disruption of Rhes farnesylation by the administration of farnesyltransferase inhibitors.

Abstract: Described herein are fabric softening compositions comprising a quaternary ammonium compound, an edible-type tallow, isopropyl alcohol, and a plasticizer comprising an iso-methyl group. Methods of making and using the fabric softening compositions are also described herein.

Abstract: Described herein are fabric softening compositions comprising a quaternary ammonium compound, an edible-type tallow, isopropyl alcohol, and a plasticizer comprising an iso-methyl group. Methods of making and using the fabric softening compositions are also described herein.

Abstract: Systems and methods for enhancing base load operation of a power system are provided. According to one embodiment of the disclosure, a method may include receiving a power production request for the power system by at least one processor. The method may also include receiving base load requirements associated with the power system. Based at least in part on the power production request, a firing temperature of the power system is modified to enhance power output of the power system while operating the power system within the base load requirements.