Patents by Inventor Israel Kleinberg

Israel Kleinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180296454
    Abstract: Compositions comprising serine and an organic mono- or multi-phosphate salt and methods of using such compositions to treat and/or prevent periodontal disease and/or dental calculus are provided.
    Type: Application
    Filed: June 21, 2018
    Publication date: October 18, 2018
    Applicant: The Research Foundation for The State University of New York
    Inventors: Israel Kleinberg, Robi Chatterjee
  • Patent number: 10076481
    Abstract: Compositions comprising serine and an organic mono- or multi-phosphate salt and methods of using such compositions to treat and/or prevent periodontal disease and/or dental calculus are provided.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: September 18, 2018
    Assignee: The Research Foundation for the State University of New York
    Inventors: Israel Kleinberg, Robi Chatterjee
  • Publication number: 20170319452
    Abstract: Compositions comprising serine and an organic mono- or multi-phosphate salt and methods of using such compositions to treat and/or prevent periodontal disease and/or dental calculus are provided.
    Type: Application
    Filed: May 4, 2017
    Publication date: November 9, 2017
    Inventors: Israel Kleinberg, Robi Chatterjee
  • Patent number: 9555057
    Abstract: A deodorant composition comprising arginine, bicarbonate, zinc and carbonate, preferably arginine bicarbonate and zinc carbonate (ABZC), and one or more physiologically acceptable excipients, administered for the modification of cutaneous microfloras—generally to reduce axillary odor, promote the growth of Staphylococcus epidermidis bacteria, inhibit the growth of Corynebacterium striatum bacteria, or any or all of the preceding.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: January 31, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Israel Kleinberg, Zegong Zhang
  • Publication number: 20160279042
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Application
    Filed: March 10, 2016
    Publication date: September 29, 2016
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Publication number: 20160263154
    Abstract: An antibacterial composition comprising arginine bicarbonate, zinc carbonate, preferably arginine bicarbonate and zinc carbonate (ABZC), in combination, plus one or more physiologically acceptable excipients, administered for the modification of cutaneous microfloras, generally to inhibit the growth of pathogenic Staphylococcus aureus bacteria by promoting the growth of non-pathogenic Staphylococcus epidermidis bacteria.
    Type: Application
    Filed: May 19, 2016
    Publication date: September 15, 2016
    Inventors: Israel Kleinberg, Zegong Zhang
  • Publication number: 20160183839
    Abstract: The invention provides a device for detecting non-cavitated caries lesions, including a measuring electrode having an electrically conductive tip. The tip is dimensionally configured to fit within a fissure and provide electrical contact with a patient's tooth. A reference electrode is also included, the reference electrode being configured for electrical contact with the patient's body. A measuring means is also provided for determining electrical conductance between the measuring electrode and the reference electrode, wherein the device is further configured to receive a current source for providing electrical current between the measuring electrode and the reference electrode.
    Type: Application
    Filed: March 7, 2016
    Publication date: June 30, 2016
    Inventors: Israel Kleinberg, Fred Confessore, Robi Chatterjee
  • Patent number: 9370476
    Abstract: A composition including arginine or a salt thereof, a zinc salt, preferably arginine bicarbonate and zinc carbonate (ABZC), in combination, plus one or more physiologically acceptable excipients, administered for the modification of cutaneous microfloras, generally to inhibit the growth of pathogenic Staphylococcus aureus bacteria and also promote the growth of non-pathogenic Staphylococcus epidermidis bacteria, and methods for using such composition.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: June 21, 2016
    Assignee: The Research Foundation for The State University of New York
    Inventors: Israel Kleinberg, Zegong Zhang
  • Publication number: 20160089315
    Abstract: A deodorant composition comprising arginine, bicarbonate, zinc and carbonate, preferably arginine bicarbonate and zinc carbonate (ABZC), and one or more physiologically acceptable excipients, administered for the modification of cutaneous microfloras—generally to reduce axillary odor, promote the growth of Staphylococcus epidermidis bacteria, inhibit the growth of Corynebacterium striatum bacteria, or any or all of the preceding.
    Type: Application
    Filed: September 29, 2015
    Publication date: March 31, 2016
    Inventors: Israel Kleinberg, Zegong Zhang
  • Publication number: 20160089395
    Abstract: An antibacterial composition comprising arginine bicarbonate, zinc carbonate, preferably arginine bicarbonate and zinc carbonate (ABZC), in combination, plus one or more physiologically acceptable excipients, administered for the modification of cutaneous microfloras, generally to inhibit the growth of pathogenic Staphylococcus aureus bacteria by promoting the growth of non-pathogenic Staphylococcus epidermidis bacteria.
    Type: Application
    Filed: September 29, 2015
    Publication date: March 31, 2016
    Inventors: Israel Kleinberg, Zegong Zhang
  • Patent number: 9277875
    Abstract: The invention provides a device for detecting non-cavitated caries lesions, including a measuring electrode having an electrically conductive tip. The tip is dimensionally configured to fit within a fissure and provide electrical contact with a patient's tooth. A reference electrode is also included, the reference electrode being configured for electrical contact with the patient's body. A measuring means is also provided for determining electrical conductance between the measuring electrode and the reference electrode, wherein the device is further configured to receive a current source for providing electrical current between the measuring electrode and the reference electrode.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: March 8, 2016
    Assignee: The Research Foundation for the State University of New York
    Inventors: Israel Kleinberg, Fred Confessore, Robi Chatterjee
  • Publication number: 20140120142
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Application
    Filed: September 23, 2013
    Publication date: May 1, 2014
    Applicant: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Publication number: 20120027828
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Application
    Filed: September 30, 2011
    Publication date: February 2, 2012
    Applicant: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Publication number: 20110111361
    Abstract: The invention provides a device for detecting non-cavitated caries lesions, including a measuring electrode having an electrically conductive tip. The tip is dimensionally configured to fit within a fissure and provide electrical contact with a patient's tooth. A reference electrode is also included, the reference electrode being configured for electrical contact with the patient's body. A measuring means is also provided for determining electrical conductance between the measuring electrode and the reference electrode, wherein the device is further configured to receive a current source for providing electrical current between the measuring electrode and the reference electrode.
    Type: Application
    Filed: November 5, 2010
    Publication date: May 12, 2011
    Applicant: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Fred Confessore, Robi Chatterjee
  • Publication number: 20080233054
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Application
    Filed: August 8, 2007
    Publication date: September 25, 2008
    Applicant: Research Foundation of State of University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Patent number: 6929790
    Abstract: The present invention relates to an oral composition containing a zinc compound containing free available zinc ion and at least one stabilized or stable Eh raising compound distributed in an oral vehicle. The present invention further relates to a method of inhibiting the formation of sulfur containing anions and preventing a reduction in the Eh of the oral cavity. A method of reducing oral malodor and gingivitis and periodontitis is also provided by this invention.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: August 16, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Milroy Codipilly
  • Publication number: 20030133885
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Application
    Filed: December 23, 2002
    Publication date: July 17, 2003
    Applicant: The Reseaarch Foundation of the State University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Patent number: 6524558
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: February 25, 2003
    Assignee: The Research Foundation of the State University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
  • Publication number: 20020182267
    Abstract: The present invention relates to an oral composition containing a zinc compound containing free available zinc ion and at least one stabilized or stable Eh raising compound distributed in an oral vehicle. The present invention further relates to a method of inhibiting the formation of sulfur containing anions and preventing a reduction in the Eh of the oral cavity. A method of reducing oral malodor and gingivitis and periodontitis is also provided by this invention.
    Type: Application
    Filed: June 24, 2002
    Publication date: December 5, 2002
    Applicant: The Research Foundation of the State University of New York at Stony Brook
    Inventors: Israel Kleinberg, Milroy Codipilly
  • Patent number: 6436370
    Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: August 20, 2002
    Assignee: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee