Patents by Inventor Israil Pendrak

Israil Pendrak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10174053
    Abstract: The compounds of the subject invention are related to 2-substituted cephem compounds, which have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: January 8, 2019
    Assignees: Glaxo Group Limited, Shionogi and Co., Ltd.
    Inventors: Toshiaki Aoki, Hiroki Kusano, Xiangmin Liao, Neil David Pearson, Israil Pendrak, Jun Sato, Reema K. Thalji, Kenji Yamawaki, Katsuki Yokoo
  • Publication number: 20170281532
    Abstract: The compounds of the subject invention are related to 2-substituted cephem compounds, which have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and pharmaceutical compositions comprising the same.
    Type: Application
    Filed: April 18, 2017
    Publication date: October 5, 2017
    Inventors: Toshiaki AOKI, Hiroki KUSANO, Xiangmin LIAO, Neil David PEARSON, Israil PENDRAK, Jun SATO, Reema K. THALJI, Kenji YAMAWAKI, Katsuki YOKOO
  • Patent number: 9340556
    Abstract: The present invention relates to cephalosporin antibacterial compounds of Formula (I): or corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods for bacterial infections, especially those caused by gram-negative bacteria.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: May 17, 2016
    Assignees: GLAXO GROUP LIMITED, SHIONOGI & CO., LTD
    Inventors: Xiangmin Liao, Neil David Pearson, Israil Pendrak, Masayuki Sano
  • Publication number: 20150299223
    Abstract: The present invention relates to 2-substituted cephem compounds of Formula (I) having a quaternary ammonium group on the 3-side chain, preferably together with a cathechol group, or pharmaceutically acceptable salts thereof, which exhibit potent antimicrobial spectrum against a variety of bacteria including Gram negative bacteria and/or Gram positive bacteria, corresponding pharmaceutical compositions, methods of making, treatment methods for bacterial infections or uses thereof.
    Type: Application
    Filed: October 29, 2013
    Publication date: October 22, 2015
    Inventors: Toshiaki AOKI, Hiroki KUSANO, Xiangmin LIAO, Neil David PEARSON, Israil PENDRAK, Jun SATO, Reema THALGI, Kenji YAMAWAKI, Katsuki YOKOO
  • Publication number: 20140249126
    Abstract: The present invention relates to cephalosporin antibacterial compounds of Formula (I): or corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods for bacterial infections, especially those caused by gram-negative bacteria.
    Type: Application
    Filed: October 4, 2012
    Publication date: September 4, 2014
    Inventors: Xiangmin Liao, Neil David Pearson, Israil Pendrak, Masayuki Sano
  • Patent number: 8071592
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 6, 2011
    Assignee: Glaxo Group Limited
    Inventors: Lluis Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J RemuiƱan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Patent number: 7691850
    Abstract: Compounds of formula (I) and derivatives thereof: compositions containing them, their preparation and their use as antibacterials.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: April 6, 2010
    Assignee: Glaxo Group Limited
    Inventors: William Henry Miller, Israil Pendrak, Mark Andrew Seefeld
  • Publication number: 20100081650
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: November 17, 2009
    Publication date: April 1, 2010
    Inventors: Jeffrey Michael Axten, Robert A. Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Patent number: 7622481
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: November 24, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Publication number: 20090270374
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 18, 2007
    Publication date: October 29, 2009
    Inventors: Llius Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A. Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J. Remuinan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B. Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Patent number: 7498326
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. The piperidine derivatives include compounds of formula (I): wherein RA, AB, n, R3, R2 and R4 are defined herein. For example, RA is an optionally substituted bicyclic carbocyclic or heterocyclic ring system, and R4 is a group U-R5 in which R5 is an optionally substituted bicyclic heterocyclic ring system as defined herein (e.g. optionally substituted pyrido [3,2, -b][1,4] thiazin-yl).
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: March 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Patent number: 7312212
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: December 25, 2007
    Assignee: Glaxo Group Limited
    Inventors: Robert A Daines, William Henry Miller, Neil David Pearson, Israil Pendrak, Mark Andrew Seefeld
  • Publication number: 20070287701
    Abstract: Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
    Type: Application
    Filed: June 15, 2005
    Publication date: December 13, 2007
    Inventors: William Miller, Israil Pendrak, Mark Seefeld
  • Patent number: 7109213
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: September 19, 2006
    Assignee: Glaxo Group Limited
    Inventors: Robert A Daines, William Henry Miller, Neil David Pearson, Israil Pendrak, Mark Andrew Seefeld
  • Publication number: 20060189604
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: June 25, 2003
    Publication date: August 24, 2006
    Inventors: Jeffrey Axten, Robert Daines, David Davies, Timothy Gallagher, Graham Jones, William Miller, Neil Pearson, Israil Pendrak
  • Publication number: 20060058287
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: June 25, 2003
    Publication date: March 16, 2006
    Inventors: Jeffrey Axten, Robert Daines, David Davies, Timothy Gallagher, Graham Jones, William Miller, Neil Pearson, Israil Pendrak
  • Publication number: 20050159411
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 27, 2003
    Publication date: July 21, 2005
    Inventors: Robert Daines, William Miller, Neil Pearson, Israil Pendrak, Mark Seefeld
  • Publication number: 20050085494
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 27, 2003
    Publication date: April 21, 2005
    Inventors: Robert Daines, William Miller, Neil Pearson, Israil Pendrak, Mark Seefeld
  • Patent number: 6608059
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: August 19, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert A. Daines, Israil Pendrak
  • Patent number: 6498187
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: February 19, 2002
    Date of Patent: December 24, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Siegfried B. Christensen, IV, Robert A. Daines, Jack D. Leber, Israil Pendrak, Joseph Weinstock