Patents by Inventor Issar Ash

Issar Ash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacturing of human mononuclear phagocytic leukocytes
    Patent number: 8377692
    Abstract: A process for the manufacture of human mononuclear phagocytic leukocytes comprises incubating monocytes isolated from a blood sample of an individual and skin segments from the same individual, removing the dermis segments from the incubation mixture and sedimenting the obtained activated mononuclear phagocytic leukocytes by centrifugation, washing and resuspending the activated phagocytic leukocytes in the medium, and evaluating the culture for its suitability for human administration. Cellular therapy products are made from the obtained cultures and are useful for promoting axonal regeneration in the CNS, wound healing and treatment of myocardial infarction.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: February 19, 2013
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Valentin Fulga, Ronit Kleiner Bakimer, Issar Ash, Michal Eisenbach-Schwartz
  • Process for the manufacturing of human mononuclear phagocytic leukocytes
    Publication number: 20050129663
    Abstract: A process for the manufacture of human mononuclear phagocytic leukocytes comprises incubating monocytes isolated from a blood sample of an individual and skin segments from the same individual, removing the dermis segments from the incubation mixture and sedimenting the obtained activated mononuclear phagocytic leukocytes by centrifugation, washing and resuspending the activated phagocytic leukocytes in the medium, and evaluating the culture for its suitability for human administration. Cellular therapy products are made from the obtained cultures and are useful for promoting axonal regeneration in the CNS, wound healing and treatment of myocardial infarction.
    Type: Application
    Filed: November 21, 2002
    Publication date: June 16, 2005
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Valentin Fulga, Ronit Kleiner Bakimer, Issar Ash, Michael Eisenbach-Schwartz