Patents by Inventor Istvan Gyoker

Istvan Gyoker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release pharmaceutical preparation and process for preparing same
    Patent number: 5324523
    Abstract: Controlled release pharmaceutical preparations are prepared by homogenizing an organic or inorganic pharmaceutical active substance such as an opium alkaloid or its salts, an opium antagonist or its salts, an aliphatic or aromatic amine derivative or its salts, a phenolate type medicament, or Zn, Fe, Mg, K, Na salts, a fatty acid or its salt necessary to achieve a continuous phase transfer and an ethylene vinyl acetate copolymer and formulating the resulting homogeneous mixture bya) direct compressing orb) admixing with a solvent orc) using a second, auxiliary polymer.The preparations are suitable for oral or rectal administration or for tissue implantation.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: June 28, 1994
    Assignee: Alkaloida Vegyeszeti Gyar
    Inventors: Miklos Zsuga, Tibor Kelen, Jozsef Nagy, Judit Barkanyi, Magdolna Bene, Sandor Ondi, Imre Gulyas, Istvan Gyoker, Janos Repasi, Agota Repasi
  • Process for the preparation of N-phosphonomethyl-glycine
    Patent number: 4486359
    Abstract: N-phosphonomethylglycine is prepared from glycine and parsformaldehyde to obtain an intermediate which is reacted with dialkylphosphite to obtain an ester of the desired compound which is then hydrolyzed.
    Type: Grant
    Filed: October 20, 1983
    Date of Patent: December 4, 1984
    Assignee: Alkaloida Vegyeszeti Gyar
    Inventors: Marta Brendel nee Hajnoczki, Imre Gulyas, Istvan Gyoker, Kalman Zsupan, Istvan Csorvassy, Zoltan Salamon, Gabor Somogyi, Istvan Szentkiralyi, Tibor Timar, E Biro nee Czapary, Istvan Fodor, Janos Repasi
  • 7,8-Dihydroisomorphine derivative, namely azidoethylmorphine
    Patent number: 4167636
    Abstract: Azidoethylmorphine, a new 7,8-dihydroisomorphine derivative, has excellent antitussive effects without respiration depression.
    Type: Grant
    Filed: March 29, 1978
    Date of Patent: September 11, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti
    Inventors: Rezso Bognar, Sandor Makleit, Geza Kiss, Sandor Berenyi, Terez Mile, Jozsef Knoll, Sandor Elek, Istvan Gyoker, Attila Zoltai, Gyorgy Toth, Laszlo Litkei
  • 6-Deoxy-6-azido-14-hydroxy-7,8-dihydroisomorphine or a pharmaceutically acceptable salt thereof
    Patent number: 4144236
    Abstract: A process for the preparation of pharmaceutically acceptable 3-protected derivatives of 6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, selected from the group which consists of 3-O-acetyl-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, 3-O-tetrahydropyranyl-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine and 3-O-methylenemethoxy-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, and the salts of these compounds which comprise the following steps:Blockin the hydroxy in position 3 of 14-hydroxy-7, 8-dihydromorphine with a moiety selected from the group which consists of acetyl, tetrahydropyranyl, and methylenemethoxy; andAzidiylating position 6 of the compounds formed in a step (a) thereby removing the hydroxy formerly in that position.
    Type: Grant
    Filed: May 10, 1977
    Date of Patent: March 13, 1979
    Assignee: Alkaloida Vegyeszeti Gyar Tiszavasvari
    Inventors: Reszo Bognar, Sandor Makleit, Geza Kiss, Sandor Berenyi, Terez Mile, Jozsef Knoll, Sandor Elek, Istvan Gyoker, Attila Zoltai, Gyorgy Toth, Laszlo Litkei