Patents by Inventor Istvan Tulok

Istvan Tulok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and reagent kit for determining activity of 5-nucleotidase
    Patent number: 6861225
    Abstract: The invention relates to a method for determining activity of 5?-nucleotidase, in which a biological sample is incubated in a manner and under conditions known per se with a nucleotide pentose monophosphate as substrate, the liberated inorganic phosphate is converted into a colored complex by treating it with ammonium molybdate and a reducing agent, color intensity is measured by a known method, and from the measured value the activity of 5?-nucle-otidase or the amount of inorganic phosphate liberated within unit time, as a figure proportional to the activity of 5?-nucleotidase, is calculated with a known calculation and/or with the aid of a calibration curve. According to the invention 5?-AMP, 5?-CMP, 5?-UMP, 5?-GMP, 5?-IMP and 5?-TMP are used as nucleotide pentose monophosphates, and measurement is performed on all of these six substrates. The invention also relates to a reagent kit for performing the above method.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: March 1, 2005
    Inventors: András Bertha, István Tulok
  • Method of alleviating toxicity originating from treatment with anticancer platinum compounds
    Patent number: 5366723
    Abstract: The present invention concerns a method of administering the amino acids L-glutamic acid, L-aspartic acid and L-cysteine for alleviating the toxicity associated with the administration of anticancer platinum compounds such as cisplatin and its derivatives.
    Type: Grant
    Filed: March 5, 1993
    Date of Patent: November 22, 1994
    Inventor: Istvan Tulok