Patents by Inventor Isuke Imada

Isuke Imada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4271083
    Abstract: Novel compounds of the formula ##STR1## wherein R represents lower alkyl or lower alkoxy, A represents --CH.sub.2 --, --CO-- or ##STR2## n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.
    Type: Grant
    Filed: November 15, 1978
    Date of Patent: June 2, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroshi Morimoto, Isuke Imada, Masazumi Watanabe, Mitsuru Kawada
  • Patent number: 4191778
    Abstract: The aqueous preparation such as an aqueous solution, a water-in-oil emulsion, in which a water-soluble salt of the quinonyl acid derivative of the formula: ##STR1## [wherein each R is a lower alkoxy group having 1 to 4 carbon atoms or the two R's, taken together, represent a group of --CH.dbd.CH--CH.dbd.CH--; --A--COOH means ##STR2## when both R's are lower alkoxy groups, or --(CH.sub.2).sub.n COOH (wherein n is an integer from 1 to 8) when two R's, taken together, represent a group of --CH.dbd.CH--CH.dbd.CH--] is dissolved in aqueous phase, shows an excellent immunoregulatory activity in animals including human being.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: March 4, 1980
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yuichi Yamamura, Ichiro Azuma, Kazuhisa Sugimura, Hiroshi Morimoto, Isuke Imada, Masazumi Watanabe
  • Patent number: 4139545
    Abstract: Novel compounds of the formulae ##STR1## wherein R represents lower alkyl or lower alkoxy, A represents --CH.sub.2 --, --CO-- or ##STR2## n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.
    Type: Grant
    Filed: April 30, 1975
    Date of Patent: February 13, 1979
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroshi Morimoto, Isuke Imada, Masazumi Watanabe, Mitsuru Kawada
  • Patent number: 4070244
    Abstract: Ubiquinone-10 is produced by culturing a microorganism belonging to the genus Sporidiobolus or Oosporidium and capable of producing ubiquinone-10, causing the microorganism to accumulate ubiquinone-10 and recovering ubiquinone-10.
    Type: Grant
    Filed: February 25, 1977
    Date of Patent: January 24, 1978
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshio Nakao, Kazuaki Kitano, Isuke Imada, Hiroshi Morimoto
  • Patent number: 3957836
    Abstract: Novel quinone derivatives of Formula ##SPC1##(wherein each R represents a lower alkyl group or a lower alkoxy group, or alternatively the R's, taken together, form -CH=CH-CH=CH-, and Z represnts hydrogen or a lower alkyl group) and pharmaceutically acceptable salts thereof exhibit excellent pharmacological activities such as vitamin-like activity, especially vitamin E-like activity, and immunosuppressive activity.
    Type: Grant
    Filed: June 28, 1974
    Date of Patent: May 18, 1976
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroshi Morimoto, Isuke Imada, Masazumi Watanabe, Mitsuru Kawada