Patents by Inventor Itai Bloch

Itai Bloch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHIONINE METABOLIC PATHWAY INHIBITORS
    Publication number: 20230250086
    Abstract: The present invention provides novel inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Application
    Filed: April 4, 2023
    Publication date: August 10, 2023
    Inventors: Itai BLOCH, Elad COHEN, Rachel AMIR, Maayan GAL
  • SULPHONAMIDES AS METHIONINE METABOLIC PATHWAY INHIBITORS
    Publication number: 20230232828
    Abstract: The present invention provides novel sulphonamide inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Application
    Filed: April 4, 2023
    Publication date: July 27, 2023
    Inventors: Itai BLOCH, Elad COHEN, Rachel AMIR, Maayan GAL
  • COMPOSITIONS COMPRISING LTB AND PATHOGENIC ANTIGENS, AND USE THEREOF
    Publication number: 20230190923
    Abstract: The present invention is directed to compositions of immunogenic polypeptides including a heat labile toxin subunit B (LTB) polypeptide and a plurality of viral polypeptides. Further provided are compositions and methods of using same, such as for vaccinating a subject in need thereof.
    Type: Application
    Filed: February 25, 2021
    Publication date: June 22, 2023
    Applicant: MIGAL GALILEE RESEARCH INSTITUTE LTD.
    Inventors: Jacob PITCOVSKI, Ehud SHAHAR, Itai BLOCH, Itamar YADID, Ran BEN ADIVA, Chen KATZ, Nady GRUZDEV
  • Sulphonamides as methionine metabolic pathway inhibitors
    Patent number: 11647748
    Abstract: The present invention provides novel sulphonamide inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: May 16, 2023
    Assignee: MIGAL—GALILEE RESEARCH INSTITUTE LTD.
    Inventors: Itai Bloch, Elad Cohen, Rachel Amir, Maayan Gal
  • Methionine metabolic pathway inhibitors
    Patent number: 11639345
    Abstract: The present invention provides novel inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: May 2, 2023
    Assignee: MIGAL—GALILEE RESEARCH INSTITUTE LTD.
    Inventors: Itai Bloch, Elad Cohen, Rachel Amir, Maayan Gal
  • PD1-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF
    Publication number: 20210284711
    Abstract: PD1-4-1BBL variant fusion proteins are provided. Also provided are isolated polypeptides comprising a PD1 variant or a 4-1BBL variant. Also provided are polynucleotides and nucleic acid constructs encoding the PD1-4-1BBL fusion protein or the isolated polypeptide, host-cells expressing the same and methods of use thereof.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 16, 2021
    Applicant: KAHR Medical Ltd.
    Inventors: Iris PECKER, Itai BLOCH
  • SIRPalpha-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF
    Publication number: 20210214417
    Abstract: SIRPalpha-4-1BBL variant fusion proteins are provided. Also provided are isolated polypeptides comprising a SIRPalpha variant. Also provided are polynucleotides and nucleic acid constructs encoding the SIRPalpha-41BBL fusion protein or the isolated polypeptide, host-cells expressing same and methods of use thereof.
    Type: Application
    Filed: July 11, 2019
    Publication date: July 15, 2021
    Applicant: KAHR Medical Ltd.
    Inventors: Iris PECKER, Itai BLOCH
  • METHIONINE METABOLIC PATHWAY INHIBITORS
    Publication number: 20200331872
    Abstract: The present invention provides novel inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Application
    Filed: July 1, 2020
    Publication date: October 22, 2020
    Inventors: Itai BLOCH, Elad COHEN, Rachel AMIR, Maayan GAL
  • SULPHONAMIDES AS METHIONINE METABOLIC PATHWAY INHIBITORS
    Publication number: 20200329705
    Abstract: The present invention provides novel sulphonamide inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.
    Type: Application
    Filed: July 1, 2020
    Publication date: October 22, 2020
    Inventors: Itai BLOCH, Elad COHEN, Rachel AMIR, Maayan GAL
  • Compositions and methods for modulating a kinase
    Patent number: 8937065
    Abstract: The invention relates to compounds and methods for modulating one or more components of a kinase signaling cascade.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: January 20, 2015
    Assignee: Clevexel Pharma
    Inventors: Oren M. Becker, Itai Bloch, Efrat Ben-Zeev, Alina Shitrit, Avihai Yacovan, Sharon Gazal, Vered Behar, Alexander Konson, Nili Schutz, Sima Mirilashvili, Gali Golan
  • Compositions and Methods for Modulating a Kinase
    Publication number: 20120316148
    Abstract: The invention relates to compounds and methods for modulating one or more components of a kinase signaling cascade.
    Type: Application
    Filed: June 7, 2012
    Publication date: December 13, 2012
    Applicant: Dynamix Pharmaceuticals LTD.
    Inventors: Oren M. Becker, Itai Bloch, Efrat Ben-Zeev, Alina Shitrit, Avihai Yacovan, Sharon Gazal, Vered Behar, Alexander Konson, Nili Schutz, Sima Mirilashvili, Gali Golan