Patents by Inventor Itai Pelled
Itai Pelled has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180263769Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.Type: ApplicationFiled: May 21, 2018Publication date: September 20, 2018Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Patent number: 10076411Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: GrantFiled: August 24, 2016Date of Patent: September 18, 2018Assignee: Edwards Lifesciences CorporationInventors: Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Patent number: 10045846Abstract: The present disclosure concerns embodiments of implantable prosthetic devices, and in particular, implantable prosthetic valves, and methods for making such devices. In one aspect, a prosthetic device includes encapsulating layers that extend over a fabric layer and secure the fabric layer to another component of the device. In particular embodiments, the prosthetic device comprises a prosthetic heart valve, and can be configured to be implanted in any of the native heart valves. In addition, the prosthetic heart valve can be, for example, a transcatheter heart valve, a surgical heart valve, or a minimally-invasive heart valve.Type: GrantFiled: April 18, 2014Date of Patent: August 14, 2018Assignee: Edwards Lifesciences CorporationInventors: Celeste C. Bonyuet, Andrew L. Walls, John F. Migliazza, Itai Pelled
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Patent number: 10028826Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: GrantFiled: August 4, 2014Date of Patent: July 24, 2018Assignee: Edwards Lifesciences CorporationInventors: Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Patent number: 9974652Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.Type: GrantFiled: May 19, 2017Date of Patent: May 22, 2018Assignee: Edwards Lifesciences CorporationInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Publication number: 20170252157Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.Type: ApplicationFiled: May 19, 2017Publication date: September 7, 2017Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Patent number: 9662204Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.Type: GrantFiled: September 11, 2014Date of Patent: May 30, 2017Assignee: Edwards Lifesciences CorporationInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Patent number: 9526813Abstract: Novel medical devices and uses thereof for lining a blood vessel and/or treating an aneurysm are disclosed herein. The device comprises a non-metallic expandable tubular structure, implantable in a body vessel and being made, at least in part, from a polymeric system characterized by a stiffness which changes upon stimulation under physiological conditions. Novel polymeric systems are further disclosed herein, which are configured to produce a polymeric material upon stimulation under physiological conditions, such that a stiffness of said polymeric material is higher than a stiffness of said system. Uses of polymer systems in the manufacture of a device are further disclosed.Type: GrantFiled: July 13, 2010Date of Patent: December 27, 2016Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Daniel Cohn, Itai Pelled, Randa Abbas, Ram Malal
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Publication number: 20160361163Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: ApplicationFiled: August 24, 2016Publication date: December 15, 2016Inventors: Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Publication number: 20160317305Abstract: The present disclosure relates to laminated sealing members for prosthetic valves and methods of making the same. In a representative embodiment, an implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.Type: ApplicationFiled: April 27, 2016Publication date: November 3, 2016Inventors: Itai Pelled, Elena Sherman, Eran Goldberg, Kevin D. Rupp, Noam Nir
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Publication number: 20150134052Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.Type: ApplicationFiled: September 11, 2014Publication date: May 14, 2015Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Patent number: 8945209Abstract: The present disclosure concerns embodiments of implantable prosthetic devices, and in particular, implantable prosthetic valves, and methods for making such devices. In one aspect, a prosthetic device includes encapsulating layers that extend over a fabric layer and secure the fabric layer to another component of the device. In particular embodiments, the prosthetic device comprises a prosthetic heart valve, and can be configured to be implanted in any of the native heart valves. In addition, the prosthetic heart valve can be, for example, a transcatheter heart valve, a surgical heart valve, or a minimally-invasive heart valve.Type: GrantFiled: May 18, 2012Date of Patent: February 3, 2015Assignee: Edwards Lifesciences CorporationInventors: Celeste C. Bonyuet, Andrew L. Walls, John F. Migliazza, Itai Pelled
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Publication number: 20140343671Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: ApplicationFiled: August 4, 2014Publication date: November 20, 2014Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Patent number: 8795357Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: GrantFiled: July 13, 2012Date of Patent: August 5, 2014Assignee: Edwards Lifesciences CorporationInventors: Ziv Yohanan, Nik Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Publication number: 20140209238Abstract: The present disclosure concerns embodiments of implantable prosthetic devices, and in particular, implantable prosthetic valves, and methods for making such devices. In one aspect, a prosthetic device includes encapsulating layers that extend over a fabric layer and secure the fabric layer to another component of the device. In particular embodiments, the prosthetic device comprises a prosthetic heart valve, and can be configured to be implanted in any of the native heart valves. In addition, the prosthetic heart valve can be, for example, a transcatheter heart valve, a surgical heart valve, or a minimally-invasive heart valve.Type: ApplicationFiled: April 18, 2014Publication date: July 31, 2014Applicant: Edwards Lifesciences CorporationInventors: Celeste C. Bonyuet, Andrew L. Walls, John F. Migliazza, Itai Pelled
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Patent number: 8454685Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.Type: GrantFiled: June 23, 2011Date of Patent: June 4, 2013Assignee: Edwards Lifesciences CorporationInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh Khanna, Son Nguyen, Tamir Levi, Itai Pelled
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Publication number: 20130018458Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.Type: ApplicationFiled: July 13, 2012Publication date: January 17, 2013Inventors: Ziv Yohanan, Nik Gurovich, Bella Felsen, Itai Pelled, Oded Meiri
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Publication number: 20120296418Abstract: The present disclosure concerns embodiments of implantable prosthetic devices, and in particular, implantable prosthetic valves, and methods for making such devices. In one aspect, a prosthetic device includes encapsulating layers that extend over a fabric layer and secure the fabric layer to another component of the device. In particular embodiments, the prosthetic device comprises a prosthetic heart valve, and can be configured to be implanted in any of the native heart valves. In addition, the prosthetic heart valve can be, for example, a transcatheter heart valve, a surgical heart valve, or a minimally-invasive heart valve.Type: ApplicationFiled: May 18, 2012Publication date: November 22, 2012Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Celeste Bonyuet, Andrew Walls, John F. Migliazza, Itai Pelled
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Publication number: 20120179193Abstract: Novel medical devices and uses thereof for lining a blood vessel and/or treating an aneurysm are disclosed herein. The device comprises a non-metallic expandable tubular structure, implantable in a body vessel and being made, at least in part, from a polymeric system characterized by a stiffness which changes upon stimulation under physiological conditions. Novel polymeric systems are further disclosed herein, which are configured to produce a polymeric material upon stimulation under physiological conditions, such that a stiffness of said polymeric material is higher than a stiffness of said system. Uses of polymer systems in the manufacture of a device are further disclosed.Type: ApplicationFiled: July 13, 2010Publication date: July 12, 2012Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Daniel Cohn, Itai Pelled, Randa Abbas, Ram Malal
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Publication number: 20110319991Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.Type: ApplicationFiled: June 23, 2011Publication date: December 29, 2011Applicant: Edwards Lifesciences CorporationInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh Khanna, Son Nguyen, Tamir Levi, Itai Pelled