Abstract: Techniques to prioritize serially transmitted data are described. The sequence of serial data segments being transmitted across a communication interface is modified such that prioritized segments that may require a higher refresh rate are transmitted more frequently than regular data segments. A prioritization configuration register can be implemented in both the transmitter and the receiver such that both sides are programmed with the altered sequence of transmission. The prioritization configuration stored in the prioritization configuration register can indicate the points in the sequence where the out-of-order transmission occurs, and which data segments are transmitted in them. The transmitter can use this information to serialize the data segments according to the prioritization, and the receiver can re-parallelize the received data as indicated by the altered sequence.