Abstract: The present invention relates to a composition which contains an intestinal bacterium belonging to the genus Veillonella and having an inflammation reducing activity, or a substance derived from the intestinal bacterium and having an inflammation reducing activity and which has at least one activity selected from an anti-inflammatory activity, an immunoregulation activity, an epithelial barrier restoring activity, an IL-10-inducing activity, and an IL-22-inducing activity, and to an ameliorating agent for an inflammatory disease, an autoimmune disease, or an infectious disease containing the intestinal bacterium and the substance derived from the intestinal bacterium and having an inflammation reducing activity.

Abstract: The present invention relates to a composition which contains an intestinal bacterium belonging to Bacteroidetes and having an inflammation reducing activity, or a substance derived from the intestinal bacterium and having an inflammation reducing activity and which has at least one activity selected from an anti-inflammatory activity, an immunoregulation activity, an epithelial barrier restoring activity, an IL-10-inducing activity, and an IL-22-inducing activity, and to an ameliorating agent for an inflammatory disease, an autoimmune disease, or an infectious disease containing the intestinal bacterium and the substance derived from the intestinal bacterium and having an inflammation reducing activity.

Abstract: A method of submerged arc welding of thick steel plates with a large heat input and flux for submerged arc welding which comprises: forming a groove having a multi-angle shape which has at least two different angular inclination when a single side submerged arc welding for perfect penetration is conducted under a condition of an welding heat input of 100 to 1000 kJ/cm; using submerged arc welding flux SiO.sub.2 : 5 to 28% by weight, MgO: 15 to 35% by weight, CaO: 5 to 15% by weight, CaF.sub.2 : 2 to 20% by weight, Al.sub.2 O.sub.3 : 5 to 15% by weight, and TiO.sub.

Abstract: A vertical down welding process by gravity arc welding, in which a guide rail 5a is disposed aslant upwardly at an inclination angle .theta..sub.1 of 40.degree. to 60.degree. to a vertical weld line 3 and, while a holder 6 of a welding rod 4 is brought down along the guide rail 5a, the welding rod 4 is moved down along the vertical weld line 3 for welding.A welding machine for use with this vertical down welding process is constructed so that the upwardly inclined guide rail 5a is provided at the inclination angle .theta..sub.1 of 40.degree. to 60.degree.;, the guide rail 5a is comprised of a main rail 5c and a sub-rail 5b; and the holder 6 of the welding rod 4 is lowered from the sub-rail 5b to the mail rail 5c.