Patents by Inventor Itay ALGOV

Itay ALGOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant flavin-adenine dinucleotide glucose dehydrogenase and uses thereof
    Patent number: 11365399
    Abstract: A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: June 21, 2022
    Assignee: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT GEN-GURION UNIVERSITY
    Inventors: Lital Alfonta, Raz Zarivach, Jennifer Grushka, Itay Algov
  • RECOMBINANT FLAVIN-ADENINE DINUCLEOTIDE GLUCOSE DEHYDROGENASE AND USES THEREOF
    Publication number: 20220162569
    Abstract: A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.
    Type: Application
    Filed: February 15, 2022
    Publication date: May 26, 2022
    Inventors: Lital ALFONTA, Raz ZARIVACH, Jennifer GRUSHKA, Itay ALGOV
  • RECOMBINANT FLAVIN-ADENINE DINUCLEOTIDE GLUCOSE DEHYDROGENASE AND USES THEREOF
    Publication number: 20210292804
    Abstract: A polypeptide comprising a residue substituted by a non-canonical amino acid (ncAA) is provided. Methods for: (a) transferring an electron to an electrode, by coupling the polypeptide to an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.
    Type: Application
    Filed: May 27, 2021
    Publication date: September 23, 2021
    Inventors: Lital ALFONTA, Raz ZARIVACH, Jennifer GRUSHKA, Itay ALGOV
  • A RECOMBINANT FLAVIN-ADENINE DINUCLEOTIDE GLUCOSE DEHYDROGENASE AND USES THEREOF
    Publication number: 20200165579
    Abstract: A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.
    Type: Application
    Filed: August 2, 2018
    Publication date: May 28, 2020
    Inventors: Lital ALFONTA, Raz ZARIVACH, Jennifer GRUSHKA, Itay ALGOV