Patents by Inventor Itsuo Nishioka

Itsuo Nishioka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antihypertensive method
    Patent number: 5358962
    Abstract: An antihypertensive method comprising administering to a hypertensive patient a pharmaceutical agent containing lithospermic acid B represented by the formula: ##STR1## and/or the pharmaceutically acceptable salt thereof, for example, Mg.sup.2+, K.sup.+, NH.sub.4.sup.+ and Ca.sup.2+ salts thereof, as an effective ingredient.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: October 25, 1994
    Assignee: Minophagen Pharmaceutical Company
    Inventors: Hikokichi Oura, Itsuo Nishioka, Takako Yokozawa, Tadao Takeuchi
  • Anti-allergic hydroxybiphenyl compounds
    Patent number: 4650813
    Abstract: New hydroxybiphenyl compounds of the general formula: ##STR1## wherein R.sub.1 stands for a hydrogen atom or a hydroxyl group, R.sub.2 for a hydrogen atom or a hydroxyl group, R.sub.3 for a hydroxyl group, a group of the formula --CH.sub.2 --CH.dbd.CH.sub.2 or a group of the formula --CH.dbd.CH--CHO, R.sub.4 for a hydrogen atom or a group of the formula ##STR2## and R.sub.5 for a hydroxyl group or a group of the formula ##STR3## These compounds are obtained by extraction of "Tokoboku", i.e. dried cortex of Magnolia officinalis which belongs to the family Magnoliaceae. They are useful as pharmaceuticals or intermediates therefor, in particular as anti-allergics.
    Type: Grant
    Filed: March 6, 1985
    Date of Patent: March 17, 1987
    Assignee: Kabushiki Kaisha Tsmurajuntendo
    Inventors: Akihide Kooda, Itsuo Nishioka, Takeshi Nishiyori, Shoji Yahara
  • Hydroxybiphenyl compounds
    Patent number: 4537996
    Abstract: New hydroxybiphenyl compounds of the general formula: ##STR1## wherein R.sub.1 stands for a hydrogen atom or a hydroxyl group, R.sub.2 for a hydrogen atom or a hydroxyl group, R.sub.3 for a hydroxyl group, a group of the formula -CH.sub.2 -CH.dbd.CH.sub.2 or a group of the formula -CH.dbd.CH-CHO, R.sub.4 for a hydrogen atom or a group of the formula ##STR2## and R.sub.5 for a hydroxyl group or a group of the formula ##STR3## These compounds are obtained by extraction of "Tokoboku", i.e. dried cortex of Magnolia officinalis which belongs to the family Magnoliaceae. They are useful as pharmaceuticals or intermediates therefor, in particular as anti-allergics.
    Type: Grant
    Filed: September 22, 1983
    Date of Patent: August 27, 1985
    Assignee: Kabushiki Kaisha Tsumurajuntendo
    Inventors: Akihide Kooda, Itsuo Nishioka, Takeshi Nishiyori, Shoji Yahara
  • Alkyl-ketohexopyranoside derivatives and method of use
    Patent number: 4395405
    Abstract: An alkyl-ketohexopyranoside derivative having pharmacological actions such as antiallergic actions, represented by the following general formula ##STR1## wherein R is an alkyl group having at least 3 carbon atoms, the derivatives excluding the D-fructose derivative wherein R is n-propyl group.
    Type: Grant
    Filed: May 15, 1980
    Date of Patent: July 26, 1983
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Akira Nakagawa, Yasushi Haraguchi, Koichiro Ueda, Munehiko Hirano, Itsuo Nishioka, Akira Yagi, Akihide Koda, Hiroyuki Ide