Patents by Inventor Itzhaq Cohen-Karni

Itzhaq Cohen-Karni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11933549
    Abstract: A high-performance thermal interface comprising a nanowire array disposed between a bottom metal layer and a top metal layer in which each nanowire is coated with a 3D fuzzy graphene layer. The thermal interface can be used by bonding it to the surfaces of adjoining substrates using layers of solder.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: March 19, 2024
    Assignee: Carnegie Mellon University
    Inventors: Sheng Shen, Wei Gong, Pengfei Li, Lin Jing, Itzhaq Cohen-Karni, Raghav Garg
  • Patent number: 9638717
    Abstract: The present invention generally relates to nanoscale wires for use in sensors and other applications. In various embodiments, a probe comprising a nanotube (or other nanoscale wire) is provided that can be directly inserted into a cell to determine a property of the cell, e.g., an electrical property. In some cases, only the tip of the nanoscale wire is inserted into the cell; this tip may be very small relative to the cell, allowing for very precise study. In some aspects, the tip of the probe is held by a holding member positioned on a substrate, e.g., at an angle, which makes it easier for the probe to be inserted into the cell. The nanoscale wire may also be connected to electrodes and/or form part of a transistor, such that a property of the nanoscale wire, and thus of the cell, may be determined. Such probes may also be useful for studying other samples besides cells.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: May 2, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: Charles M. Lieber, Ruixuan Gao, Steffen Strehle, Xiaojie Duan, Bozhi Tian, Itzhaq Cohen-Karni, Ping Xie, Quan Qing
  • Publication number: 20160282303
    Abstract: The present invention generally relates to nanoscale devices and methods, including bent nanowires and other bent nanoscale objects, and in particular, the ability to probe cells with nanoscale objects. In some aspects, nanoscale objects, including nanowires, are provided that facilitate cell probing, e.g. nanowires that are surface modified such that cells can fuse with the nanowires. Devices including nanoscale objects are provided that allow small or large scale (e.g., multiplexed) probing of cells, and related methods of making such nanoscale objects and devices, and methods of investigating cells, are provided by certain embodiments of the invention. In a related set of embodiments, the present invention is generally related to bent nanowires and other bent nanoscale objects. For instance, in one aspect, the present invention is generally related to a semiconductor nanoscale wire having at least one kink. The semiconductor nanoscale wire may be formed out of any suitable semiconductor, e.g.
    Type: Application
    Filed: February 18, 2016
    Publication date: September 29, 2016
    Inventors: Charles M. Lieber, Bozhi Tian, Ping Xie, Thomas J. Kempa, Itzhaq Cohen-Karni, Quan Qing, Xiaojie Duan
  • Patent number: 9297796
    Abstract: Kinked nanowires are used for measuring electrical potentials inside simple cells. An improved intracellular entrance is achieved by modifying the kinked nanowires with phospholipids.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: March 29, 2016
    Assignee: President and Fellows of Harvard College
    Inventors: Bozhi Tian, Ping Xie, Thomas J. Kempa, Charles M. Lieber, Itzhaq Cohen-Karni, Quan Qing, Xiaojie Duan
  • Publication number: 20150137794
    Abstract: The present invention generally relates to nanoscale wires for use in sensors and other applications. In various embodiments, a probe comprising a nanotube (or other nanoscale wire) is provided that can be directly inserted into a cell to determine a property of the cell, e.g., an electrical property. In some cases, only the tip of the nanoscale wire is inserted into the cell; this tip may be very small relative to the cell, allowing for very precise study. In some aspects, the tip of the probe is held by a holding member positioned on a substrate, e.g., at an angle, which makes it easier for the probe to be inserted into the cell. The nanoscale wire may also be connected to electrodes and/or form part of a transistor, such that a property of the nanoscale wire, and thus of the cell, may be determined. Such probes may also be useful for studying other samples besides cells.
    Type: Application
    Filed: May 2, 2013
    Publication date: May 21, 2015
    Inventors: Charles M. Lieber, Ruixuan Gao, Steffen Strehle, Xiaojie Duan, Bozhi Tian, Itzhaq Cohen-Karni, Ping Xie, Quan Qing
  • Publication number: 20120267604
    Abstract: Kinked nanowires are used for measuring electrical potentials inside simple cells. An improved intracellular entrance is achieved by modifying the kinked nanowires with phospholipids.
    Type: Application
    Filed: September 24, 2010
    Publication date: October 25, 2012
    Inventors: Bozhi Tian, Ping Xie, Thomas J. Kempa, Charles M. Lieber, Itzhaq Cohen-Karni, Quan Qing, Xiaojie Duan