Patents by Inventor Iulia Sacui

Iulia Sacui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor
    Patent number: 10851407
    Abstract: A method of making optically pure preparations of chiral ?PNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral ?PNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed ?PNA, and vice-versa, are provided.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: December 1, 2020
    Assignee: Carnegie Mellon University
    Inventors: Danith H. Ly, Wei-Che Hsieh, Iulia Sacui, Arunava Manna
  • Left-Handed Gamma-Peptide Nucleic Acids, Methods of Synthesis and Uses Therefor
    Publication number: 20170058325
    Abstract: A method of making optically pure preparations of chiral ?PNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral ?PNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed ?PNA, and vice-versa, are provided.
    Type: Application
    Filed: May 8, 2015
    Publication date: March 2, 2017
    Inventors: Danith H. Ly, Wei-Che Hsieh, Iulia Sacui, Arunava Manna