Patents by Inventor Iva Benko

Iva Benko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-oxa-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the production thereof
    Patent number: 7232815
    Abstract: The present invention relates to derivatives of 1-oxa-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory actions, especially to the inhibition of tumour necrosis factor-? (TNF-?) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: June 19, 2007
    Assignee: GlaxoSmithKline
    Inventors: Mladen Mercep, Milan Mesic, Dijana Pesic, Iva Benko
  • Thiadibenzoazulene derivatives for the treatment of inflammatory diseases
    Publication number: 20060069149
    Abstract: The present invention relates to (a) novel 1-thiadibenzoazulene derivatives of the formula (I), (b) to their pharmacologically acceptable esters, salts and solvates, (c) to processes and intermediates for the preparation thereof, (d) to a process for preparing pharmaceutical formulations for the treatment of inflammatory diseases and conditions and (e) to the use thereof in the treatment of inflammatory diseases and conditions in humans and animals. These compounds inhibit tumour necrosis factor-? (TNF-?) production and interleukin-1 (IL-1) production and exhibit an analgetic action.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 30, 2006
    Applicant: Pliva-Istrazivacki Institut d.o.o.
    Inventors: Mladen Mercep, Milan Mesic, Dijana Pesic, Iva Benko
  • 1-Oxa-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the production thereof
    Publication number: 20050148576
    Abstract: The present invention relates to derivatives of 1-oxa-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory actions, especially to the inhibition of tumour necrosis factor-? (TNF-?) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
    Type: Application
    Filed: April 9, 2003
    Publication date: July 7, 2005
    Applicant: Pliva-Istrazivacki Institut d.o.o.
    Inventors: Mladen Mercep, Milan Mesic, Dijana Pesic, Iva Benko
  • 1-oxa 3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the production thereof
    Publication number: 20050130956
    Abstract: The present invention relates to derivatives of 1-oxa-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory actions, especially to the inhibition of tumour necrosis factor-? (TNF-?) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
    Type: Application
    Filed: October 13, 2004
    Publication date: June 16, 2005
    Applicant: Pliva-Istrazivacki Institut d.o.o.
    Inventors: Mladen Mercep, Milan Mesic, Dijana Pesic, Iva Benko