Patents by Inventor Ivan D. MASCANFRONI

Ivan D. MASCANFRONI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS OF TREATING AUTOIMMUNE DISEASES
    Publication number: 20200069731
    Abstract: Embodiments of various aspects described herein are directed to methods and compositions for producing a tolerogenic or immunosuppressive dendritic cell. In particular, an immunosuppressive dendritic cell can be produced by contacting a dendritic cell with an agent that stimulates the IL-27/ectonucleotidase CD39 axis signaling. In some embodiments, the methods and/or compositions described herein can be used for treating an autoimmune disease or disorder, e.g., but not limited to multiple sclerosis (MS) and type 1 diabetes.
    Type: Application
    Filed: September 30, 2019
    Publication date: March 5, 2020
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Francisco J. QUINTANA, Ivan D. MASCANFRONI
  • Methods and compositions of treating autoimmune diseases
    Patent number: 10426794
    Abstract: Embodiments of various aspects described herein are directed to methods and compositions for producing a tolerognic or immunosuppressive dendritic cell. In particular, an immunosuppressive dendritic cell can be produced by contacting a dendritic cell with an agent that stimulates the IL 27/ectonucleotidase CD39 axis signaling. In some embodiments, the methods and/or compositions described herein can be used for treating an autoimmune disease or disorder, e.g., but not limited to multiple sclerosis (MS) and type 1 diabetes.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: October 1, 2019
    Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Francisco J. Quintana, Ivan D. Mascanfroni
  • METHODS AND COMPOSITIONS OF TREATING AUTOIMMUNE DISEASES
    Publication number: 20160058792
    Abstract: Embodiments of various aspects described herein are directed to methods and compositions for producing a tolerogenic or immunosuppressive dendritic cell. In particular, an immunosuppressive dendritic cell can be produced by contacting a dendritic cell with an agent that stimulates the IL 27/ectonucleotidase CD39 axis signaling. In some embodiments, the methods and/or compositions described herein can be used for treating an autoimmune disease or disorder, e.g., but not limited to multiple sclerosis (MS) and type 1 diabetes.
    Type: Application
    Filed: April 11, 2014
    Publication date: March 3, 2016
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Francisco J. QUINTANA, Ivan D. MASCANFRONI