Patents by Inventor Ivan Dmochowski

Ivan Dmochowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transcriptome in vivo analysis
    Patent number: 9540634
    Abstract: Provided are compositions and methods that permit a hybrid nucleic acid-peptide molecule to enter a cell and when specifically activated within the cell, the molecule anneals to endogenous cellular RNA and permits the isolation of the RNA.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: January 10, 2017
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: James Eberwine, Ditte Lovatt, Julia Richards, Ivan Dmochowski, Brittani Ruble
  • Transcriptome in vivo analysis
    Patent number: 9540680
    Abstract: The invention provides compositions and methods that permit a hybrid nucleic acid molecule to enter a cell and when specifically activated within the cell, the molecule anneals to endogenous cellular RNA and permits the isolation of the RNA.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 10, 2017
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: James Eberwine, Ditte Lovatt, Julia Richards, Ivan Dmochowski, Brittani Ruble
  • Photocleavable oligonucleotide and uses thereof
    Patent number: 9371348
    Abstract: This invention relates to methods and compositions of oligonucleotide constructs having a photocleavable linker. Specifically, provided herein are methods and compositions utilizing a photocleavable linker, which when exposed to light modulates the expression of genes.
    Type: Grant
    Filed: November 27, 2007
    Date of Patent: June 21, 2016
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Ivan Dmochowski, XinJing Tang
  • Transcriptome In Vivo Analysis
    Publication number: 20130273537
    Abstract: The invention provides compositions and methods that permit a hybrid nucleic acid molecule to enter a cell and when specifically activated within the cell, the molecule anneals to endogenous cellular RNA and permits the isolation of the RNA.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 17, 2013
    Inventors: James Eberwine, Ditte Lovatt, Julia Richards, Ivan Dmochowski, Brittani Ruble
  • TRANSCRIPTOME IN VIVO ANALYSIS
    Publication number: 20130267678
    Abstract: Provided are compositions and methods that permit a hybrid nucleic acid-peptide molecule to enter a cell and when specifically activated within the cell, the molecule anneals to endogenous cellular RNA and permits the isolation of the RNA.
    Type: Application
    Filed: June 7, 2011
    Publication date: October 10, 2013
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: James Eberwine, Ditte Lovatt, Julia Richards, Ivan Dmochowski, Brittani Ruble
  • Xe biosensors and their use
    Patent number: 8470587
    Abstract: This invention relates to enzyme-sensitive biosensors and methods and kits using the same. Specifically, the invention relates to methods, systems and kits for the detection of enzymes using the chemical shift observed in an isotope complexed to the biosensor resulting from a change in the biosensor as the result of the enzyme's activity.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: June 25, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Ivan Dmochowski, Qian Wei, Nicholas Kuzma, P. Aru Hill
  • Tri-functionalized cryptophane biosensors
    Patent number: 8222022
    Abstract: This invention relates to biosensors with improved solubility and affinity to a noble element. Specifically, the invention relates to methods and systems for the detection of target entities using the signal observed in a noble element complexed to the biosensor.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: July 17, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Ivan Dmochowski, Aru P. Hill, Qian Wei, Jennifer M. Chambers
  • 129Xe BIOSENSORS AND THEIR USE
    Publication number: 20110104075
    Abstract: This invention relates to enzyme-sensitive biosensors and methods and kits using the same. Specifically, the invention relates to methods, systems and kits for the detection of enzymes using the chemical shift observed in an isotope complexed to the biosensor resulting from a change in the biosensor as the result of the enzyme's activity.
    Type: Application
    Filed: August 6, 2007
    Publication date: May 5, 2011
    Inventors: Ivan Dmochowski, Qian Wei, Nicholas Kuzma, Aru P. Hill
  • TRI-FUNCTIONALIZED CRYPTOPHANE, SYNTHESIS AND USES THEREOF
    Publication number: 20100105099
    Abstract: This invention relates to biosensors with improved solubility and affinity to a noble element. Specifically, the invention relates to methods and systems for the detection of target entities using the signal observed in a noble element complexed to the biosensor.
    Type: Application
    Filed: July 7, 2009
    Publication date: April 29, 2010
    Inventors: Ivan Dmochowski, Aru P. Hill, Qian Wei, Jennifer M. Chambers
  • Photocleavable oligonucleotide and uses thereof
    Publication number: 20080227742
    Abstract: This invention relates to methods and compositions of oligonucleotide constructs having a photocleavable linker. Specifically, provided herein are methods and compositions utilizing a photocleavable linker, which when exposed to light modulates the expression of genes.
    Type: Application
    Filed: November 27, 2007
    Publication date: September 18, 2008
    Inventors: Ivan Dmochowski, XinJing Tang
  • Detection of biomolecules by sensitizer-linked substrates
    Publication number: 20070112180
    Abstract: Methods and compositions for detecting and characterizing target biomolecules using sensitizer-linked substrate molecules are disclosed. High throughput screening assays and therapeutic applications of the inventions are also included.
    Type: Application
    Filed: August 29, 2006
    Publication date: May 17, 2007
    Inventors: Harry Gray, Brian Crane, Jay Winkler, Ivan Dmochowski, Jonathan Wilker, Alexander Dunn