Patents by Inventor Ivan HLAVACEK

Ivan HLAVACEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS OF PREPARING IOSIMENOL
    Publication number: 20220048852
    Abstract: The present invention relates to a 5-step process for preparing iosimenol starting from ammonium 3-amino-5-(aminocarbonyl)benzoate which is first converted to 3-amino-5-(aminocarbonyl)-2,4,6-triiodobenzoic acid using sodium iodine dichloride (NaICl2). The present invention further relates to processes for purifying iosimenol.
    Type: Application
    Filed: October 22, 2021
    Publication date: February 17, 2022
    Inventors: Jiri MALINAK, Ivan HLAVACEK, Petr ZAHRADNIK
  • PROCESS OF PREPARING IOSIMENOL
    Publication number: 20200095191
    Abstract: The present invention relates to a 5-step process for preparing iosimenol starting from ammonium 3-amino-5-(aminocarbonyl)benzoate which is first converted to 3-amino-5-(aminocarbonyl)-2,4,6-triiodobenzoic acid using sodium iodine dichloride (NaI—Cl2). The present invention further relates to processes for purifying iosimenol.
    Type: Application
    Filed: April 27, 2018
    Publication date: March 26, 2020
    Inventors: Jiri MALINAK, Ivan HLAVACEK, Petr ZAHRADNIK
  • Innovative preparation and crystallization of iosimenol
    Patent number: 10544089
    Abstract: The present invention generally relates to a process of preparing iosimenol and a process of preparing a crystal of iosimenol, as well as a crystal of iosimenol prepared by these processes.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: January 28, 2020
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Jiri Malinak, Ivan Hlavacek, Jiri Prokop, Yoshito Masuda
  • IOHEXOL POWDER AND METHOD OF USING THE SAME
    Publication number: 20190298862
    Abstract: Iohexol particles, contrast agent compositions comprising iohexol particles, methods of preparing iohexol particles, and methods of administering iohexol particles are provided herein. The iohexol particles of the present invention substantially dissolve in water within about 60 seconds when tested using Modified United States Pharmacopeia Method 641.
    Type: Application
    Filed: June 5, 2019
    Publication date: October 3, 2019
    Applicant: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Jirí PROKOP, Ivan HLAVÁCEK, Petr ZAHRADNÍK, Jirí MALINAK
  • INNOVATIVE PREPARATION AND CRYSTALLIZATION OF IOSIMENOL
    Publication number: 20190177266
    Abstract: The present invention generally relates to a process of preparing iosimenol and a process of preparing a crystal of iosimenol, as well as a crystal of iosimenol prepared by these processes.
    Type: Application
    Filed: November 2, 2016
    Publication date: June 13, 2019
    Inventors: Jiri MALINAK, Ivan HLAVACEK, Jiri PROKOP, Yoshito MASUDA
  • IOHEXOL POWDER AND METHOD OF USING THE SAME
    Publication number: 20150251993
    Abstract: Iohexol particles, contrast agent compositions comprising iohexol particles, methods of preparing iohexol particles, and methods of administering iohexol particles are provided herein. The iohexol particles of the present invention substantially dissolve in water within about 60 seconds when tested using Modified United States Pharmacopeia Method 641.
    Type: Application
    Filed: March 4, 2015
    Publication date: September 10, 2015
    Inventors: Jirí PROKOP, Ivan HLAVÁCEK, Petr ZAHRADNÍK, Jirí MALINAK