Patents by Inventor Ivan K. Chu

Ivan K. Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequencing of peptides by mass spectrometry
    Patent number: 6799121
    Abstract: A strategy for semiautomatic sequencing of argentinated (silver-containing) oligopeptides is described. The method of sequencing described is based on a search algorithm that identifies a triplet peak relationship in a product ion spectrum of the [M+Ag]+ ion of an oligopeptide. The ions that constitute a triplet are [bn+OH+Ag]+, [bn−H+Ag]+, and [an−H+Ag]+, which are separated by 18 and 28 m/z units, respectively. The difference in the m/z values of adjacent triplets identifies the residue that is “cleaved”. Observation of the [yn+H+Ag]+ ion containing the cleaved residue confirms the assignment.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: September 28, 2004
    Assignee: York University
    Inventors: Ivan K. Chu, Tai-Chu Lau, K. W. Michael Siu
  • Sequencing of peptides by mass spectrometry
    Publication number: 20020001814
    Abstract: A strategy for semiautomatic sequencing of argentinated (silver-containing) oligopeptides is described. The method of sequencing described is based on a search algorithm that identifies a triplet peak relationship in a product ion spectrum of the [M+Ag]+ ion of an oligopeptide. The ions that constitute a triplet are [bn+OH+Ag]+, [bn−H+Ag]+, and [an−H+Ag]+, which are separated by 18 and 28 m/z units, respectively. The difference in the m/z values of adjacent triplets identifies the residue that is “cleaved”. Observation of the [yn+H+Ag]+ ion containing the cleaved residue confirms the assignment.
    Type: Application
    Filed: March 13, 2001
    Publication date: January 3, 2002
    Applicant: YORK UNIVERSITY
    Inventors: Ivan K. Chu, Tai-Chu Lau, K. W. Michael Siu