Patents by Inventor Ivan Labat

Ivan Labat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the Diagnosis and Treatment of Preeclampsia
    Publication number: 20090280124
    Abstract: Provided by the present invention are methods for treating and diagnosing preeclampsia, as well as kits for use in diagnosing patients with a higher risk of preeclampsia.
    Type: Application
    Filed: November 10, 2008
    Publication date: November 12, 2009
    Applicant: HERA BIOMEDICAL INC.
    Inventors: Ivan Labat, Birgit Stache-Crain, Y. Tom Tang, Bryan J. Boyle, Susan Andarmani
  • Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080241207
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 19, 2007
    Publication date: October 2, 2008
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080241882
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes fro producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 16, 2007
    Publication date: October 2, 2008
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same
    Publication number: 20080227200
    Abstract: A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells and cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.
    Type: Application
    Filed: November 26, 2007
    Publication date: September 18, 2008
    Inventors: Radoje T. Drmanac, Ivan Labat, Y. Tom Tang, Juhi Lee, Birgit Stache-Crain, Mitsuo Nishikawa
  • Novel nucleic acids and polypeptides
    Publication number: 20080050393
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 22, 2002
    Publication date: February 28, 2008
    Inventors: Y. Tom Tang, Vinod Asundi, Dennis Ballinger, Ivan Labat, Dena Leshkowitz, Jin Liu, Deborah Loeb, Julia R. Montgomery, Ann M. Pace, James P. Sheridan, Radoje T. Drmanac
  • Stem cell growth factor-like polypeptides
    Patent number: 7319141
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: January 15, 2008
    Assignees: Kirin Beer Kabushiki Kaisha, Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy K. Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Polynucleotides encoding stem cell growth factor-like polypeptides
    Patent number: 7317099
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: December 23, 2000
    Date of Patent: January 8, 2008
    Assignee: Kirin Pharma Kabushiki Kaisha
    Inventors: Ivan Labat, Y. Tom Tang, Radoje T. Drmanac, Chenghua Liu, Juhi Lee, Nancy K. Mize, John Childs, Cheng-Chi Chao
  • Human genes and gene expression products
    Publication number: 20070243176
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.
    Type: Application
    Filed: July 7, 2003
    Publication date: October 18, 2007
    Inventors: Jaime Escobedo, Pablo Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Filippo Randazzo, George Lamson, Elizabeth Scott, Guozhong Zhang, Altaf Kassam, David Pot, Radoje Drmanac, Ivan Labat, Birgit Stache-Crain
  • Human genes and gene expression products V
    Patent number: 7122373
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: October 17, 2006
    Assignee: Nuvelo, Inc.
    Inventors: Lewis T. Williams, Jaime Escobedo, Michael A. Innis, Pablo Dominguez Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Klaus Giese, Filippo Randazzo, Giulia C. Kennedy, David Pot, Altaf Kassam, George Lamson, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee William Jones, Birgit Stache-Crain
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20060074044
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof the correspond to a novel human secreted stem cell growth factor-like polypeptide. These polypeptides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invertion include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 18, 2005
    Publication date: April 6, 2006
    Applicant: Nuvelo
    Inventors: Ivan Labat, Y. Tang, Radoje Drmanac, Chenghua Liu, Juhi Lee, Nancy Mize, John Childs, Cheng-Chi Chao
  • Methods and diagnosis for the treatment of preeclampsia
    Publication number: 20050255114
    Abstract: Provided by the present invention are methods for treating and diagnosing preeclampsia, as well as kits for use in diagnosing patients with a higher risk of preeclampsia.
    Type: Application
    Filed: April 7, 2004
    Publication date: November 17, 2005
    Applicant: NUVELO, Inc.
    Inventors: Ivan Labat, Y. Tang, Birgit Stache-Crain, Bryan Boyle
  • Human genes and gene expression products II
    Patent number: 6964868
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: November 15, 2005
    Assignee: Nuvelo, Inc.
    Inventors: Lewis T. Williams, Jaime Escobedo, Michael A. Innis, Pablo Dominguez Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Klaus Giese, Filippo Randazzo, Giulia C. Kennedy, David Pot, Altaf Kassam, George Lamson, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee William Jones, Birgit Stache-Crain
  • Gene products differentially expressed in cancerous cells and their methods of use II
    Publication number: 20050227917
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Application
    Filed: February 12, 2004
    Publication date: October 13, 2005
    Inventors: Lewis Williams, Jaime Escobedo, Michael Innis, Pablo Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Klaus Giese, Filippo Randazzo, Giulia Kennedy, David Pot, Altaf Kassam, George Lamson, Zhijun He, Elizabeth Scott, Guozhong Zhang, Theresa May, Doreen Sakamoto, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee Jones, Birgit Stache-Crain
  • Method and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20050059073
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: October 19, 2004
    Publication date: March 17, 2005
    Inventors: Y. Tang, Ivan Labat, Radoje Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide
    Patent number: 6824973
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: November 30, 2004
    Assignees: Kirin Beer Kabushiki Kaisha, Nuvelo Inc.
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Methods and materials relating to soluble transforming growth factor alpha-like polypeptides and polynucleotides
    Publication number: 20040132022
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted TGF alpha-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human adult kidney (Hyseq clone identification number 16441036). Other aspects of the invention include vectors containing processes for producing novel human secreted TGF alpha-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 1, 2004
    Publication date: July 8, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, Servando Palencia, Y Tom Tang, Chenghua Liu, Radoje T. Drmanac, Ivan Labat, Birgit Stache-Crain, Kody Nguyen, Veronica E. Garcia
  • Human genes and gene expression products XVI
    Publication number: 20040086913
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.
    Type: Application
    Filed: June 26, 2003
    Publication date: May 6, 2004
    Inventors: Lewis T. Williams, Jaime Escobedo, Michael A. Innis, Pablo Dominguez Garcia, Julie Sudduth Klinger, Christoph Reinhard, Zhijun He, Filippo Randazzo, Giulia C. Kennedy, David Pot, Altaf Kassam, George Lamson, Radjoe Drmanac, Mark Dickson, Ivan Labat, Lee William Jones, Birgit Stache-Crain
  • Stem cell growth factor-like polypeptides
    Patent number: 6673904
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human and mouse secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from mouse bone marrow and human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, placental, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: January 6, 2004
    Assignees: Kirin Beer Kabushiki Kaisha, Hyseq, Inc.
    Inventors: Mitsuo Nishikawa, Ivan Labat, Radoje T. Drmanac, Y. Tom Tang, Cheng-Chi Chao, Nancy Mize, John Childs
  • Stem cell growth factor-like polypeptide
    Patent number: 6667391
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: December 23, 2003
    Inventors: Radoje T. Drmanac, Ivan Labat, Y. Tom Tang, Cheng-Chi Chao, Nancy K. Mize, John Childs
  • Human genes and gene expression products isolated from human prostate
    Publication number: 20030215803
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostics and therapeutics comprising such novel human polynucleotides, their corresponding genes or gene products, including probes, antisense nucleotides, and antibodies. The polynucleotides of the invention correspond to a polynucleotide comprising the sequence information of at least one of SEQ ID NOS: 1-1477. The polypeptides of the invention correspond to a polypeptide comprising the amino acid sequence information of at least one of SEQ ID NOS: 1478-1568.
    Type: Application
    Filed: December 7, 2001
    Publication date: November 20, 2003
    Inventors: Pablo Dominguez Garcia, Jaime Escobedo, Altaf Kassam, George Lamson, Elizabeth Scott, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee William Jones, Birgit Stache-Crain