Patents by Inventor Ivan Mikkelsen

Ivan Mikkelsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl derivates, their preparation and use
    Patent number: 7393845
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Indole derivatives
    Patent number: 7342015
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 11, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20080027071
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 31, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Mario Rottlander, Ejner Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Novel indole derivatives
    Publication number: 20060258678
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 27, 2002
    Publication date: November 16, 2006
    Inventors: Mario Rottländer, Ejner Moltzen, Ivan Mikkelsen, Thomas Tuhland, Kim Andersen, Christian Krog-Jensen
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20040248883
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: July 6, 2004
    Publication date: December 9, 2004
    Inventors: Mario Rottlander, Ejner K. Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Indole and 2,3-dihydroindole derivatives, their preparation and use
    Patent number: 6727263
    Abstract: The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) or any of its any of its enantiometers or any mixture thereof, or an acid addition salt thereof, wherein A, R1, R2, R3, W, X, Y and Z are as described in the description. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: April 27, 2004
    Assignee: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Jens Kristian Perregaard, Ivan Mikkelsen, Garrick Paul Smith
  • Indane or dihydroindole derivatives
    Patent number: 6552044
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I) wherein A is an indole. These compounds have high affinity for D4 receptors.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: April 22, 2003
    Assignee: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Benny Bang-Andersen, Henrik Pedersen, Ivan Mikkelsen, Robert Dancer
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20030050306
    Abstract: A heteroaryl derivative having the formula (I) 1
    Type: Application
    Filed: June 25, 2002
    Publication date: March 13, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Ivan Mikkelsen, Mario Rottlander, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Indole and 2,3-dihydroindole derivatives, their preparation and use
    Publication number: 20030018050
    Abstract: The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) 1
    Type: Application
    Filed: August 16, 2002
    Publication date: January 23, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Jens Kristian Perregaard, Ivan Mikkelsen, Garrick Paul Smith
  • Indole and 2,3-dihydroindole derivatives, their preparation and use
    Patent number: 6476035
    Abstract: The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) or any of its any of its enantiometers or any mixture thereof, or an acid addition salt thereof, wherein A, R1, R2, R3, W, X, Y and Z are as described in the description. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
    Type: Grant
    Filed: January 25, 2000
    Date of Patent: November 5, 2002
    Inventors: Ejner Knud Moltzen, Jens Kristian Perregaard, Ivan Mikkelsen, Garrick Paul Smith
  • 4,5,6, and 7-indole and indoline derivatives, their preparation and use
    Publication number: 20020128272
    Abstract: A substituted 4-, 5-, 6-, and 7-indole derivative of Formula (I) 1
    Type: Application
    Filed: January 15, 2002
    Publication date: September 12, 2002
    Applicant: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Ivan Mikkelsen, Christian Krog-Jensen
  • Indane or dihydroindole derivatives
    Patent number: 6436940
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I), wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: August 20, 2002
    Assignee: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Ivan Mikkelsen, Henrik Pedersen
  • 4,5,6 and 7-indole and indoline derivatitives, their preparation and use
    Patent number: 6391882
    Abstract: A substituted 4-, 5-, 6-, and 7-indole derivative of Formula (I) wherein A is a group having formula (IIA), (IIB), (IIC) wherein X, U, Y, R3 to R12, Z, W, n and m are as defined above. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: May 21, 2002
    Assignee: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Ivan Mikkelsen, Christian Korg-Jensen
  • Indane or dihydroindole derivatives
    Patent number: 6352988
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I) wherein A is an indole. These compounds have high affinity for D4 receptors.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: March 5, 2002
    Assignee: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Benny Bang-Andersen, Henrik Pedersen, Ivan Mikkelsen, Robert Dancer
  • Indane or dihydroindole derivatives
    Patent number: 6331544
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I), wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: December 18, 2001
    Assignee: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Ivan Mikkelsen, Henrik Pedersen
  • Indane or dihydroindole derivatives
    Publication number: 20010051625
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of 1
    Type: Application
    Filed: July 26, 2001
    Publication date: December 13, 2001
    Applicant: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Ivan Mikkelsen, Henrik Pedersen
  • Indane or dihydroindole derivatives
    Publication number: 20010020095
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I) 1
    Type: Application
    Filed: March 21, 2001
    Publication date: September 6, 2001
    Applicant: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Benny Bang-Andersen, Henrik Pedersen, Ivan Mikkelsen, Robert Dancer
  • Indane or dihydroindole derivatives
    Patent number: 6262087
    Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I) wherein A is an indole. These compounds have high affinity for D4 receptors.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: July 17, 2001
    Assignee: H. Lundbeck A/S
    Inventors: Jens Kristian Perregaard, Benny Bang-Andersen, Henrik Pedersen, Ivan Mikkelsen, Robert Dancer