Patents by Inventor Ivan R. Nabi

Ivan R. Nabi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of an AMF ligand and a cytotoxic molecule for use in cancer therapy
    Publication number: 20030223978
    Abstract: The present invention relates to a therapeutical conjugate to specifically kill motile cells, which comprises a first molecule which binds to autocrine motility factor receptor (AMF-R) attached to a second toxic molecule to kill said motile cells.
    Type: Application
    Filed: February 14, 2003
    Publication date: December 4, 2003
    Inventor: Ivan R. Nabi
  • Method of determining metastatic potential of bladder tumor cells
    Patent number: 5650500
    Abstract: Methods and compositions useful in the detection of human cancer cells and malignant tumors are provided. Certain human autocrine motility factor receptors or proteins (gp78-hAMFR) have been identified which are useful in the detection of human cancer cells and malignant tumors. Methods and assay kits for the detection of human cancer, human cancer cells, and tumors, are provided wherein antibodies or nucleotide hybridized probes are used to determine gp78-hAMFR expression. These methods and assays readily distinguish between non-malignant and malignant cancer cells and tumors and can be used to gauge metastatic potential.
    Type: Grant
    Filed: July 27, 1994
    Date of Patent: July 22, 1997
    Assignee: Barbara Ann Karmanos Cancer Institute
    Inventors: Avraham Raz, Ivan R. Nabi, Hideomi Watanabe, Thomas Otto
  • Method of determining metastatic potential of tumor cells
    Patent number: 5541298
    Abstract: Methods and compositions useful in the detection of human cancer cells and malignant tumors are provided. Certain human autocrine motility factor receptors or proteins (gp78-hAMFR) have been identified which are useful in the detection of human cancer cells and malignant tumors. Methods and assay kits for the detection of human cancer, human cancer cells, and tumors, are provided wherein antibodies or other probes are used which recognize gp78-hAMFR expression. These methods and assay readily distinguish between non-malignant and malignant cancer cells and tumors and can be used to gauge metastatic potential.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 30, 1996
    Assignee: Michigan Cancer Foundation
    Inventors: Avraham Raz, Ivan R. Nabi, Hideomi Watanabe, Thomas Otto
  • Method of determining metastatic potential of bladder tumor cells
    Patent number: 5382521
    Abstract: Methods and compositions useful in the screening of human bladder cancer cells and malignant tumors are provided. Certain human autocrine motility factor receptors or proteins (gp78-hAMFR) have been identified which are useful in the screening of human bladder cancer cells and malignant tumors. Methods and assay kits for the screening of human bladder cancer, human cancer cells, and tumors, are provided wherein antibodies or other probes are used which recognize gp78-hAMFR expression. These methods and assays readily distinguish between non-malignant and malignant cancer cells and tumors and can be used to gauge metastatic potential.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: January 17, 1995
    Assignee: Michigan Cancer Foundation
    Inventors: Avraham Raz, Ivan R. Nabi, Hideomi Watanabe, Thomas Otto