Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g.

Abstract: Automated data analytics techniques for non-tabular data sets may include methods and systems for (1) automatically developing models that perform tasks in the domains of computer vision, audio processing, speech processing, text processing, or natural language processing; (2) automatically developing models that analyze heterogeneous data sets containing image data and non-image data, and/or heterogeneous data sets containing tabular data and non-tabular data; (3) determining the importance of an image feature with respect to a modeling task, (4) explaining the value of a modeling target based at least in part on an image feature, and (5) detecting drift in image data. In some cases, multi-stage models may be developed, wherein a pre-trained feature extraction model extracts low-, mid-, high-, and/or highest-level features of non-tabular data, and a data analytics models uses those features (or features derived therefrom) to perform a data analytics task.

Abstract: A system and method for capturing automation data from an automated system uses a multi-array populated by an automation controller with automation data including timing data defined by a controller clock. The multi-array includes at least one member corresponding to a sensor sensing a state of the member and a plurality of member-defined data elements, which may correspond to a start time and end time of the member state. Automation data is captured from the controller multi-array by a computing device in communication with the controller including a first data table corresponding with the controller multi-array for efficient collection of the automation data from the controller memory, and a second data table for associating each data element with its defining member and storing the associated data in a historical database which may be used for analysis of cycle time data of a member, device or operation of the automated system.

Abstract: Therapy regimes of a plurality of subjects are remotely monitored and/or managed, wherein the therapy regimes include reception of aerosolized medicament. This enables users such as medical care providers, researchers, clinic administrators, and/or other users to monitor and/or manage the therapy regimes of the plurality of subjects through a centralized access point. This reduces physical requirements of proximity for the users and/or the subjects, alleviates the administrative the burden placed on the users to manage and/or monitor individual therapy regimes, and/or provides other enhancements over convention systems.

Abstract: A system and method for capturing automation data from an automated system uses a multi-array populated by an automation controller with automation data including timing data defined by a controller clock. The multi-array includes at least one member corresponding to a sensor sensing a state of the member and a plurality of member-defined data elements, which may correspond to a start time and end time of the member state. Automation data is captured from the controller multi-array by a computing device in communication with the controller including a first data table corresponding with the controller multi-array for efficient collection of the automation data from the controller memory, and a second data table for associating each data element with its defining member and storing the associated data in a historical database which may be used for analysis of cycle time data of a member, device or operation of the automated system.

Abstract: A system and method for capturing automation data from an automated system uses a multi-array populated by an automation controller with automation data including timing data defined by a controller clock. The multi-array includes at least one member corresponding to a sensor sensing a state of the member and a plurality of member-defined data elements, which may correspond to a start time and end time of the member state. Automation data is captured from the controller multi-array by a computing device in communication with the controller including a first data table corresponding with the controller multi-array for efficient collection of the automation data from the controller memory, and a second data table for associating each data element with its defining member and storing the associated data in a historical database which may be used for analysis of cycle time data of a member, device or operation of the automated system.

Abstract: A method for enhancing in situ bioremediation of a volume containing groundwater and a quantity of contaminant, the method comprising the steps of: quantifying the mass of the contaminant; and amending the volume by adding thereto a compound that provides a source of NO3?. The method is characterized in that the compound is added such that the mass of the NO3? source is provided at the ratio of about 1 mg NO3? per 0.21 mg contaminant. The contaminant can be BTEX or petroleum-related VOC.

Abstract: A method for enhancing in situ bioremediation of a volume containing groundwater and a quantity of contaminant, the method comprising the steps of: quantifying the mass of the contaminant; and amending the volume by adding thereto a compound that provides a source of NO3?. The method is characterized in that the compound is added such that the mass of the NO3? source is provided at the ratio of about 1 mg NO3? per 0.21 mg contaminant. The contaminant can be BTEX or petroleum-related VOC.

Abstract: The composition comprises, by mass, about: 52% Lactose, 15.2% B12-fortified Brewer's Yeast, 12% Sodium Proponate, 0.8% Sodium carbonate, 0.12% Nitrate Nitrogen, 2.1% Ammoniacal Nitrogen, 3.78% Urea Nitrogen, 1% Available Phosphoric Acid, 0.4% Soluble Potash (K2O), 2% Sulphur (S), 0.0064% Iron, 0.0066% Manganese, 0.0036% Zinc, 0.00068% Copper, 0.003% Boron and about 0.0068% Molybdenum.

Abstract: A method and apparatus includes detecting lightning induced electromagnetic pulses and determining a physical property of an underground structure based on the lightning induced electromagnetic pulses. In some embodiments, an apparatus includes an antenna, a low noise amplifier, a processor, cable, and a transmitter. The antenna includes three substantively perpendicular loops of electrical conductors. The processor is configured to condition the amplified signal. The cable is about 100 meters in length and connects the low noise amplifier to the processor. The transmitter is configured to send conditioned data to a data aggregation system.

Abstract: Techniques for a receiver includes a low noise amplifier, a Q-enhanced bandpass filter on a chip, and an analog to digital converter (ADC) at a sub-sampling speed suitable for an intermediate frequency (IF) signal. In some embodiments, a temperature compensation circuit is included. The receiver has an effective noise level less than 7 dB. In some embodiments a 1-bit ADC is used. In some of these embodiments, one or more switches in the ADC are inverted to cancel charge injection.

Abstract: Therapy regimes of a plurality of subjects are remotely monitored and/or managed, wherein the therapy regimes include reception of aerosolized medicament. This enables users such as medical care providers, researchers, clinic administrators, and/or other users to monitor and/or manage the therapy regimes of the plurality of subjects through a centralized access point. This reduces physical requirements of proximity for the users and/or the subjects, alleviates the administrative the burden placed on the users to manage and/or monitor individual therapy regimes, and/or provides other enhancements over convention systems.

Abstract: Techniques for an analog-to-digital converter (ADC) using pipeline architecture includes a linearization technique for a spurious-free dynamic range (SFDR) over 80 deciBels. In some embodiments, sampling rates exceed a megahertz. According to a second approach, a switched-capacitor circuit is configured for correct operation in a high radiation environment. In one embodiment, the combination yields high fidelity ADC (>88 deciBel SFDR) while sampling at 5 megahertz sampling rates and consuming <60 milliWatts. Furthermore, even though it is manufactured in a commercial 0.25-?m CMOS technology (1 ?m=12?6 meters), it maintains this performance in harsh radiation environments. Specifically, the stated performance is sustained through a highest tested 2 megarad(Si) total dose, and the ADC displays no latchup up to a highest tested linear energy transfer of 63 million electron Volts square centimeters per milligram at elevated temperature (131 degrees C.) and supply (2.7 Volts, versus 2.5 Volts nominal).

Abstract: A method for enhancing anaerobic reductive dechlorination of a contaminated site includes enriching the site with organic carbon suitable for use as an energy source by dechlorinating bacteria, nitrogen in the form of urea or ammonia, nutrient phosphorus, matter that releases bio-available hydrogen over a relatively short period of time and relatively quickly following site enrichment and matter that releases bio-available hydrogen over a relatively long period of time following site enrichment.

Abstract: Techniques for an analog-to-digital converter (ADC) using pipeline architecture includes a linearization technique for a spurious-free dynamic range (SFDR) over 80 deciBels. In some embodiments, sampling rates exceed a megahertz. According to a second approach, a switched-capacitor circuit is configured for correct operation in a high radiation environment. In one embodiment, the combination yields high fidelity ADC (>88 deciBel SFDR) while sampling at 5 megahertz sampling rates and consuming <60 milliWatts. Furthermore, even though it is manufactured in a commercial 0.25-?m CMOS technology (1 ?m=12?6 meters), it maintains this performance in harsh radiation environments. Specifically, the stated performance is sustained through a highest tested 2 megarad(Si) total dose, and the ADC displays no latchup up to a highest tested linear energy transfer of 63 million electron Volts square centimeters per milligram at elevated temperature (131 degrees C.) and supply (2.7 Volts, versus 2.5 Volts nominal).