Patents by Inventor Ivan Smirnov

Ivan Smirnov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSING IDH1 RELATED SUBGROUPS AND TREATMENT OF CANCER
    Publication number: 20200340066
    Abstract: The invention relates to classification, diagnosis and treatment of cancers. In one embodiment, the present invention provides methods and kits that classify cancers into various subtypes based on expression patterns of AKT pathway components. In another embodiment, the present invention provides methods and kits that diagnose cancer subtypes by evaluating expression patterns of AKT pathway components. In still another embodiment, the present invention provides methods and kits that treat a cancer subtype by administering an alkylating agent or a PI3K/AKT/mTOR inhibitor to a patient. Cancers suitable with various embodiments of the invention include but are not limited to brain tumors, gliomas and GBM.
    Type: Application
    Filed: July 8, 2020
    Publication date: October 29, 2020
    Applicant: Dignity Health
    Inventors: Anna Joy, Burt G. Feuerstein, Ivan Smirnov
  • Diagnosing IDH1 related subgroups and treatment of cancer
    Patent number: 10731221
    Abstract: The invention relates to classification, diagnosis and treatment of cancers. In one embodiment, the present invention provides methods and kits that classify cancers into various subtypes based on expression patterns of AKT pathway components. In another embodiment, the present invention provides methods and kits that diagnose cancer subtypes by evaluating expression patterns of AKT pathway components. In still another embodiment, the present invention provides methods and kits that treat a cancer subtype by administering an alkylating agent or a PI3K/AKT/mTOR inhibitor to a patient. Cancers suitable with various embodiments of the invention include but are not limited to brain tumors, gliomas and GBM.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: August 4, 2020
    Assignee: Dignity Health
    Inventors: Anna Joy, Burt G. Feuerstein, Ivan Smirnov
  • DIAGNOSING IDH1 RELATED SUBGROUPS AND TREATMENT OF CANCER
    Publication number: 20150354012
    Abstract: The invention relates to classification, diagnosis and treatment of cancers. In one embodiment, the present invention provides methods and kits that classify cancers into various subtypes based on expression patterns of AKT pathway components. In another embodiment, the present invention provides methods and kits that diagnose cancer subtypes by evaluating expression patterns of AKT pathway components. In still another embodiment, the present invention provides methods and kits that treat a cancer subtype by administering an alkylating agent or a PI3K/AKT/mTOR inhibitor to a patient. Cancers suitable with various embodiments of the invention include but are not limited to brain tumors, gliomas and GBM.
    Type: Application
    Filed: August 14, 2015
    Publication date: December 10, 2015
    Applicant: DIGNITY HEALTH
    Inventors: Anna Joy, Burt G. Feuerstein, Ivan Smirnov
  • LIPOSOMES CONTAINING OLIGOPEPTIDE FRAGMENTS OF MYELIN BASIC PROTEIN, A PHARMACEUTICAL COMPOSITION AND A METHOD FOR TREATMENT OF MULTIPLE SCLEROSIS
    Publication number: 20130058994
    Abstract: The present invention provides compositions and methods for the treatment of multiple sclerosis. Among others, the invention provides compositions of immunodominant peptides of myelin basic protein encapsulated in mannosylated liposomes. In a specific embodiment, the compositions comprise mylein basic protein (MBP) peptides MBP(46-62), MBP(124-139), and MBP(147-170).
    Type: Application
    Filed: April 11, 2012
    Publication date: March 7, 2013
    Inventors: Alexander Gabivov, Alexey Belogurov, Natalia Ponomarenko, Ivan Smirnov, Andrew Bacon, Gregory Gregoriadis