Patents by Inventor Ivo Boneca

Ivo Boneca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof
    Publication number: 20090017073
    Abstract: A method for modulating Nod1 activity wherein said method comprises the steps of providing cells expressing a functional Nod1: and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis.
    Type: Application
    Filed: June 5, 2008
    Publication date: January 15, 2009
    Inventors: Philippe Sansonetti, Stephen Girardin, Dana Philpott, Ivo Boneca
  • Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof
    Patent number: 7396812
    Abstract: A method for modulating Nod1 activity wherein said method comprises the steps of providing cells expressing a functional Nod1; and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: July 8, 2008
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Philippe Sansonetti, Stephen Girardin, Dana Philpott, Ivo Boneca
  • Use of enzymes from Helicobacter pylori as therapeutical targets
    Publication number: 20070042448
    Abstract: Methods for identifying molecules which inhibit the virulence or pathogenicity of Helicobacter pylori by modulating the activity of hydrolases encoded by genes amiA, mltD and slt. Compositions and diagnostic and treatment methods using hydrolases and molecules which inhibit them.
    Type: Application
    Filed: June 2, 2006
    Publication date: February 22, 2007
    Applicant: INSTITUTE PASTEUR
    Inventors: Ivo Boneca, Catherine Chaput
  • Method for modulating nod1 activity, use of a mtp related molecule for modulating nod1 activity, and therapeutic applications thereof
    Publication number: 20060217319
    Abstract: A method for modulating Nod1 activity wherein said method comprises the steps of providing cells expressing a functional Nod1; and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis.
    Type: Application
    Filed: March 29, 2004
    Publication date: September 28, 2006
    Inventors: Philippe Sansonetti, Stephen Girardin, Dana Philpott, Ivo Boneca
  • Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof
    Patent number: 7078165
    Abstract: A method for modulating Nod 1 activity wherein said method comprises the steps of providing cells expressing a functional Nod 1; and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: July 18, 2006
    Assignee: Institut Pasteur
    Inventors: Stephen Girardin, Dana Philpott, Philippe Sansonetti, Ivo Boneca
  • Modulation of interaction between Nod1 and Gram-negative bacteria by Nod1 response to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island (cagPAI)
    Publication number: 20060084090
    Abstract: A method for identifying a compound that modulates the interaction between Nod1 and a Gram-negative bacteria comprising contacting a Nod1 expressing cell with a cagPAI-positive H. pylori in the presence of a compound, contacting a Nod1 expressing cell with a cagPAI-positive H. pylori in the absence of said compound, and detecting the activation of a pro-inflammatory factor and/or the production of a pro-inflammatory cytokine or chemokine, wherein altered activation and/or production indicates that said compound modulates the interaction between Nod1 and the Gram-negative bacteria. The method is useful for identifying compounds for regulating the signaling cascade involving Nod1 against Gram-negative bacteria that cause mucosal inflammation in animal hosts.
    Type: Application
    Filed: August 3, 2005
    Publication date: April 20, 2006
    Inventors: Richard Ferrero, Dana Philpott, Jerome Viala, Ivo Boneca, Catherine Chaput, Stephen Girardin
  • Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof
    Publication number: 20040235735
    Abstract: A method for modulating Nod 1 activity wherein said method comprises the steps of providing cells expressing a functional Nod 1; and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis
    Type: Application
    Filed: March 25, 2004
    Publication date: November 25, 2004
    Inventors: Stephen Girardin, Dana Philpott, Philippe Sansonetti, Ivo Boneca