Abstract: In the present disclosure, an artificial joint shell includes a base and a coating film. The base has a cup shape and includes an outer surface including a first region and a second region adjacent to the first region. The coating film contains a calcium phosphate-based material and an antimicrobial material and is disposed across the first region and the second region of the outer surface of the base. A surface of the coating film in the first region has a larger surface roughness than a surface of the coating film in the second region.

Abstract: In the present disclosure, an artificial joint stem includes a base including one or more grooves disposed on a surface of the base, and a coating film containing a calcium phosphate-based material and an antimicrobial material disposed on a part of the surface of the base. When among the one or more grooves, the groove located in a region where the coating film is disposed is defined as a first groove, and the groove located in a region where the surface of the base is exposed is defined as a second groove, a total length of the first groove is smaller than a total length of the second groove.

Abstract: In the present disclosure, an artificial joint stem includes a base having an outer surface including a rough surface, and a coating film disposed on the rough surface of the base and containing a calcium phosphate-based material and an antimicrobial agent. The rough surface includes an exposed region exposed from the coating film.

Abstract: In the present disclosure, an artificial joint stem includes a base extending in a vertical direction when a proximal side of a human body in use is defined as an upward direction, and a coating film containing a calcium phosphate-based material and an antimicrobial material disposed on a part of the base. The base includes one or more boundary lines on the base defined by a presence or absence of the coating film. The one or more boundary lines include a first boundary line located on a lower side of the base with respect to the coating film. The first boundary line is located so as to intersect the vertical direction. A component along the vertical direction of the first boundary line is smaller than a component along a width direction of the base.

Abstract: In the present disclosure, an artificial joint stem includes a base and a coating film located on the base. The base includes a first region, a second region, and a third region located in sequence. The coating film contains a calcium phosphate-based material and an antimicrobial material. The coating film is located across the first region and the second region, and the third region is exposed from the coating film. The surface of the coating film located in the first region has a larger surface roughness than the surface of the base in the third region.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 90% or less is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film. If necessary, a metal oxide layer made of a metal oxide having an isoelectric point of less than 7 is formed on the bioimplant thereby suppressing adhesion of bacteria.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 90% or less is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film. If necessary, a metal oxide layer made of a metal oxide having an isoelectric point of less than 7 is formed on the bioimplant thereby suppressing adhesion of bacteria.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 90% or less is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film. If necessary, a metal oxide layer made of a metal oxide having an isoelectric point of less than 7 is formed on the bioimplant thereby suppressing adhesion of bacteria.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: Provided is a bioimplant superior in antimicrobial action and safety in the body. The bioimplant according to the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal spraying film is 0.02 wt % to 3.00 wt %.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 90% or less is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film. If necessary, a metal oxide layer made of a metal oxide having an isoelectric point of less than 7 is formed on the bioimplant thereby suppressing adhesion of bacteria.

Abstract: The present invention provides a biomedical implant material comprising a substrate for biomedical implant made of a ceramic material, a first coating layer formed on the surface of said substrate by low-thermal impact coating process, and a second coating layer formed on said first coating layer via a metallic layer formed by thermal spraying process, and a method of producing the same. According to the biomedical implant material, it is made possible to prevent cracks from occurring in the ceramic substrate, and to secure sufficient bonding strength between the thermal-sprayed layer of titanium or the like onto the ceramic substrate.

Abstract: The present invention provides a biomedical implant material comprising a substrate for biomedical implant made of a ceramic material, a first coating layer formed on the surface of said substrate by low-thermal impact coating process, and a second coating layer formed on said first coating layer via a metallic layer formed by thermal spraying process, and a method of producing the same. According to the biomedical implant material, it is made possible to prevent cracks from occurring in the ceramic substrate, and to secure sufficient bonding strength between the thermal-sprayed layer of titanium or the like onto the ceramic substrate.