Patents by Inventor Iwona Gawronska

Iwona Gawronska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence of dsRNA: ATN-RNA specific for tenascin-C
    Patent number: 8946400
    Abstract: The subject matters of this invention are a sequence of double-stranded RNA: ATN-RNA, intervention using interference RNA (iRNAi), use of a sequence of double-stranded RNA: ATN-RNA, a method of treating a brain tumor and a method of inhibiting a brain tumor cells which express tenascin, a kit for inhibiting cancer cell which expresses tenascin and a method for a kit preparation in a brain tumor therapy. Malignant gliomas preferentially express a number of surface markers that may be exploited as therapeutic targets, including tenascin-C, an extracellular matrix glycoprotein that is ubiquitously expressed by malignant gliomas and probably contributes to tumor cell adhesion, invasion, migration and proliferation. For tenascin-C inhibition, RNA interference intervention (iRNAi) approach have been applied.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: February 3, 2015
    Assignees: Instytut Chemii Bioorganicznej Pan, Uniwersytet Medyczny Im.Karola Marcinkowskiego, Bioinfobank Sp.Z O.O.
    Inventors: Jan Barciszewski, Miroslawa Barciszewska, Leszek Rychlewski, Eliza Wyszko, Iwona Gawronska, Ryszard Zukiel, Katarzyna Rolle, Stanisaw Nowak
  • SEQUENCE OF DSRNA: ATN-RNA, INTERVENTION USING IRNAI, USE OF A SEQUENCE OF DSRNA: ATN-RNA, A METHOD OF TREATING AND INHIBITING A BRAIN TUMOR, A KIT FOR INHIBITING CANCER CELL WHICH EXPRESSES TENASCIN, A METHOD FOR A KIT PREPARATION IN A BRAIN TUMOR THERAPY
    Publication number: 20100076053
    Abstract: The subject matters of this invention are a sequence of double-stranded RNA: ATN-RNA, intervention using interference RNA (iRNAi), use of a sequence of double-stranded RNA: ATN-RNA, a method of treating a brain tumor and a method of inhibiting a brain tumor cells which express tenascin, a kit for inhibiting cancer cell which expresses tenascin and a method for a kit preparation in a brain tumor therapy. Malignant gliomas preferentially express a number of surface markers that may be exploited as therapeutic targets, including tenascin-C, an extracellular matrix glycoprotein that is ubiquitously expressed by malignant gliomas and probably contributes to tumor cell adhesion, invasion, migration and proliferation. For tenascin-C inhibition, RNA interference intervention (iRNAi) approach have been applied.
    Type: Application
    Filed: July 30, 2007
    Publication date: March 25, 2010
    Applicants: INSTYTUT CHEMII BIOORGANICZNEJ PAN, BIOINFOBANK SP. Z O.O., UNIWERSYTET MEDYCZNY IM.KAROLA MARCINKOWSKIEGO
    Inventors: Jan Barciszewski, Miroslawa Barciszewska, Leszek Rychlewski, Eliza Wyszko, Iwona Gawronska, Ryszard Zukiel, Katarzyna Rolle, Stanisaw Nowak