Patents by Inventor Izabela K. Sibilska

Izabela K. Sibilska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-METHYLENE ANALOGS OF CALCITRIOL AND RELATED COMPOUNDS
    Publication number: 20170253546
    Abstract: Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1?-hydroxy-2-methylene-vitamin D3, (20S)-1?-hydroxy-2-methylene-vitamin D3, and (5E)-1?,25-dihydroxy-2-methylene-vitamin D3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.
    Type: Application
    Filed: May 18, 2017
    Publication date: September 7, 2017
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Izabela K. Sibilska, Rafal R. Sicinski, Lori A. Plum
  • Synthesis and biological activity of 2-methylene analogs of calcitriol and related compounds
    Patent number: 9688596
    Abstract: Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1?-hydroxy-2-methylene-vitamin D3, (20S)-1?-hydroxy-2-methylene-vitamin D3, and (5E)-1?,25-dihydroxy-2-methylene-vitamin D3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: June 27, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Izabela K. Sibilska, Rafal R. Sicinski, Lori A. Plum
  • SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-METHYLENE ANALOGS OF CALCITRIOL AND RELATED COMPOUNDS
    Publication number: 20170036977
    Abstract: Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1?-hydroxy-2-methylene-vitamin D3, (20S)-1?-hydroxy-2-methylene-vitamin D3, and (5E)-1?,25-dihydroxy-2-methylene-vitamin D3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.
    Type: Application
    Filed: July 26, 2016
    Publication date: February 9, 2017
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Izabela K. Sibilska, Rafal R. Sicinski, Lori A. Plum