Patents by Inventor Izhack Cherny

Izhack Cherny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
    Patent number: 10688330
    Abstract: A genetically modified polypeptide is disclosed which comprises an amino acid sequence of phosphotriesterase (PTE) having at least twice the catalytic efficiency for a V-type nerve agent as a polypeptide which consists of the sequence as set forth in SEQ ID NO: 1, when assayed under identical conditions.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: June 23, 2020
    Assignees: Yeda Research and Development Co. Ltd., University of Washington
    Inventors: Dan S. Tawfik, Haim Leader, Yaacov Ashani, Izhack Cherny, Moshe Goldsmith, Per Jr. Greisen, Sagar D. Khare, Gustav Oberdorfer, David Baker, Sarel Fleishman, Adi Goldenzweig, Nidhi Aggarwal
  • Antibacterial agents and methods of identifying and utilizing same
    Patent number: 7625707
    Abstract: A method of identifying a molecule capable of inducing death of a bacterial cell which includes exposing toxin and antitoxin polypeptides of a toxin-antitoxin pair produced by the bacterial cell to a plurality of molecules, and identifying a molecule of the plurality of molecules capable of preventing or disrupting binding between the antitoxin and said toxin polypeptides, thereby identifying the molecule capable of inducing death of the bacterial cell.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 1, 2009
    Assignee: Ramot At Tel Aviv University Ltd.
    Inventors: Ehud Gazit, Izhack Cherny
  • Use of anti-amyloid agents for treating and typing pathogen infections
    Publication number: 20090156471
    Abstract: A method of preventing or treating a pathogen infection in a subject is provided. The method comprising administering to a subject in need thereof a therapeutically effective amount of an anti amyloid agent, thereby treating or preventing the pathogen infection in the subject.
    Type: Application
    Filed: July 14, 2005
    Publication date: June 18, 2009
    Applicant: RAMOT AT TEL AVIV UNIVERSITY LTD.
    Inventors: Ehud Gazit, Izhack Cherny
  • Novel Antibacterial Agents and Methods of Identifying and Utilizing Same
    Publication number: 20070298043
    Abstract: A method of identifying a molecule capable of inducing death of a bacterial cell which includes exposing toxin and antitoxin polypeptides of a toxin-antitoxin pair produced by the bacterial cell to a plurality of molecules, and identifying a molecule of the plurality of molecules capable of preventing or disrupting binding between the antitoxin and said toxin polypeptides, thereby identifying the molecule capable of inducing death of the bacterial cell.
    Type: Application
    Filed: September 27, 2004
    Publication date: December 27, 2007
    Inventors: Ehud Gazit, Izhack Cherny