Abstract: An explosively propelled piston assembly (EPPA) comprising an optional mounting plate; at least one lower cylinder fastener; a breach bolt with a base and an upward extending member; a breach plate having a plurality of surround openings; a breach gasket having a plurality of openings; a combustion piston with a base, a center opening, and upward extending side wall and a threaded opening; a piston dampening ring; a combustion cylinder having an upper section, a lower section, upward extending members and at least one ventilation bore; and a plurality of threaded plate fasteners. Once the EPPA is assembled, an explosive charge is placed into the EPPA. The charge is then activated which produces a contained explosive force that actuates the piston, causing the piston to extend outward, applying the force onto an object in contact with or adjacent to the EPPA. The force can be used to produce pushing, flipping, rolling or other movement of the object.

Abstract: An explosively propelled piston assembly (EPPA) comprising an optional mounting plate; at least one lower cylinder fastener; a breach bolt with a base and an upward extending member; a breach plate having a plurality of surround openings; a breach gasket having a plurality of openings; a combustion piston with a base, a center opening, and upward extending side wall and a threaded opening; a piston dampening ring; a combustion cylinder having an upper section, a lower section, upward extending members and at least one ventilation bore; and a plurality of threaded plate fasteners. Once the EPPA is assembled, an explosive charge is placed into the EPPA. The charge is then activated which produces a contained explosive force that actuates the piston, causing the piston to extend outward, applying the force onto an object in contact with or adjacent to the EPPA. The force can be used to produce pushing, flipping, rolling or other movement of the object.

Abstract: In one aspect, the invention provides liquid stable formulations of antithrombin.

Abstract: In one aspect, the disclosure provides formulations that stabilize proteins, wherein the formulations comprise a buffer. In some embodiments, the buffer comprises potassium mono-hydrogen-phosphate and potassium di-hydrogen-phosphate, or the buffer comprises sodium mono-hydrogen-phosphate and sodium di-hydrogen-phosphate. In some embodiments, the protein is a therapeutic protein. In some embodiments, the therapeutic protein is antithrombin.

Abstract: A method, system and computer program product for determining a response to a sales event within a time period with information which spans across hierarchical entity boundaries of a company. The method detects a sales event and determines requirements of the sales event, parties involved and resource area of the sales event. If the resource area is not supported by the company, return to detecting another sales event without responding to the sales event. If the area is supported by the company, initiating a sales resource optimization to determine an optimized resource package to respond to the sales event and determining a likelihood of the company being awarded the sales event based on the optimized resource package. If the likelihood of the company being awarded the sales event based on the optimized resource package is greater than a predetermined probability, responding to the sales event with the optimized resource package.

Abstract: A method of permitting controlled access to medical information can include establishing a storage means for containing medical information and establishing a means for accessing the medical information. The method further can include controlling the means for accessing the medical information according to a type of entity accessing the medical information, wherein access is limited according to the type of entity.

Abstract: A flesh illuminating device (FID) (10) that is comprised of three major elements: an electronic control unit (ECU) (12), an LED assembly (50) and a flesh attachment assembly (70). The ECU (12) and the LED assembly (50) are attached to the flesh attachment assembly (70) which is dimensioned to allow the LED assembly (50) to be attached to a selectable section of flesh. The section of flesh can consist of either an arm, a hand, a leg, a foot, at least one ear lobe or at least one breast. When the FID (10) is manually or remotely turned ON, the LED assembly (50) which preferably consists of at least one LED (60), illuminates causing the selected section of flesh to illuminate.

Abstract: A continually improving method for providing information to receivers which can include the step of receiving a request from a remotely located information requestor that specifies at least one information receiver. A transaction can be initiated to handle the request. The transaction can utilize previously recorded information to determine at least one adjustable condition to be used. The previously recorded information can be specific to the information requestor and/or the information receiver. The transaction can generate at least one result for the information receiver. The generated result can be tailored for information privileges granted to the information receiver by an information controller. The result can be conveyed to the information receiver. Feedback can be received concerning the result. At least one of the adjustable conditions can be adjusted in accordance with the feedback. The recorded information can be changed to include the adjusted condition.

Abstract: In one aspect, the invention provides liquid stable formulations of antithrombin.

Abstract: A method and system for generating codified electronic records. A textual commentary can be received from a user and, in real time, the textual commentary can be analyzed to identify a plurality of codes that potentially correlate to the textual commentary. The identified codes then can be presented to the user in real time. A first user input can be received to select at least one of the identified codes, and the selected code can be added to an electronic record.

Abstract: A method of representing a subject genome can include comparing the subject genome to a base reference genome and identifying a difference between the subject genome and the base reference genome. The method can further include assigning one or more items of descriptive information to the difference, and compiling the items into a data set, where the data set represents the subject genome.

Abstract: Content such as computer software, data representing audiovisual works, and electronic documents can converted from a machine-bound state to user-bound state without modification to the content data itself. Instead, keys used to access the content are converted from the machine-bound state to the user-bound state. In particular, the keys are kept in a passport data structure which can represent either a machine-binding or a user-binding. A machine-bound passport can be upgraded to a user-bound passport without modifying the bound content. The private key of the machine-bound passport, in cleartext form, is included in the user-bound passport and encrypted using a user-supplied password to bind the private key to the user. In addition, private user information is collected and verified and included in the user-bound passport.

Abstract: A cancer test having prognostic utility in predicting time to disease progression, overall survival, and response to therapy in patients with MBC based upon the presence and number of CTC's. The Cell Spotter® System is used to enumerate CTC's in blood. The system immunomagnetically concentrates epithelial cells, fluorescently labels the cells and identifies and quantifies CTC's. The absolute number of CTC's detected in the peripheral blood tumor load is, in part, a factor in prediction of survival, time to progression, and response to therapy. The mean time to survival of patients depended upon a threshold number of 5 CTC's per 7.5 ml of blood. Detection of CTC's in metastatic cancer represents a novel prognostic factor in patients with metastatic cancers, suggests a biological role for the presence of tumor cells in the blood, and indicates that the detection of CTC's could be considered an appropriate surrogate marker for prospective therapeutic clinical trials.

Abstract: A method of creating a container of data entails selecting data to be included in the container, displaying a graphical representation of the container and displaying additional detail of the container depending upon the device on which the container is displayed and synchronizing the data in the container with a master container when possible. As part of the graphical representation of the container, graphical representations related to the media related data may be displayed and the graphical representation may be of a card that might fit in a wallet.

Abstract: A method for providing information to a receiver can include the step of receiving a request from a remotely located information requestor that specifics an information receiver: initiating a transaction to handle the request utilizing previously recorded information that can be specific to the information requestor or receiver to determine at least one adjustable condition used by the transaction: the transaction generating at least one result for the information receiver, which is tailored for information privileges granted to the information receiver by an information controller: conveying the result to the information receiver: receiving feedback concerning the result from the information requestor or receiver; adjusting one of the at least one adjustable condition in accordance with the feedback: changing the recorded information to include the adjusted condition; and using the adjusted condition in handling a subsequent request by the information requestor that specifies the information receiver.

Abstract: A continually improving method for providing information to receivers which can include the step of receiving a request from a remotely located information requestor that specifies at least one information receiver. A transaction can be initiated to handle the request. The transaction can utilize previously recorded information to determine at least one adjustable condition to be used. The previously recorded information can be specific to the information requestor and/or the information receiver. The transaction can generate at least one result for the information receiver. The generated result can be tailored for information privileges granted to the information receiver by an information controller. The result can be conveyed to the information receiver. Feedback can be received concerning the result. At least one of the adjustable conditions can be adjusted in accordance with the feedback. The recorded information can be changed to include the adjusted condition.

Abstract: Chain-drive systems and methods of operation are described that allow chain travel along a non-linear path. In one example, the chain-drive system comprises a chain guide defining a channel having at least one non-linear region. A chain, sized to move within the channel, is driven by a drive sprocket. In one example, the non-linear region could redirect the chain 180 degrees and obviate the need for an idler sprocket. In another example, two channels are defined in the chain guide, including regions wherein the channels are parallel and regions where they have an angularly skewed relationship.