Patents by Inventor J. Antoni Rafalski

J. Antoni Rafalski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11053554
    Abstract: A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyses of the genome are used to predict the degree of a heterotic phenotype in plants. In some examples, copy number variation is used to predict the degree of heterotic phenotype. In some methods copy number variation is detected using competitive genomic hybridization arrays. Further, methods for optimizing the arrays are disclosed, together with kits for producing such arrays, as well as hybrid plants selected for development based on the predicted results.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: July 6, 2021
    Inventors: Mary Beatty, James A. Janni, Jonathan E. Lightner, J. Antoni Rafalski
  • Patent number: 10316370
    Abstract: Compositions and methods useful in identifying and selecting maize plants with increased ear weight and yield are provided herein. The methods use molecular genetic markers to identify and/or select maize plants with increased ear weight and increased yield or to identify and counter-select maize plants with decreased ear weight and decreased yield.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: June 11, 2019
    Assignees: E I DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Steven R. Anderson, Ada S. Ching, Stanley Luck, J. Antoni Rafalski
  • Publication number: 20180142309
    Abstract: A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyses of the genome are used to predict the degree of a heterotic phenotype in plants. In some examples, copy number variation is used to predict the degree of heterotic phenotype. In some methods copy number variation is detected using competitive genomic hybridization arrays. Further, methods for optimizing the arrays are disclosed, together with kits for producing such arrays, as well as hybrid plants selected for development based on the predicted results.
    Type: Application
    Filed: January 22, 2018
    Publication date: May 24, 2018
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: MARY BEATTY, JAMES A. JANNI, JONATHAN E. LIGHTNER, J. ANTONI RAFALSKI
  • Publication number: 20170306420
    Abstract: Compositions and methods useful in identifying and selecting maize plants with increased ear weight and yield are provided herein. The methods use molecular genetic markers to identify and/or select maize plants with increased ear weight and increased yield or to identify and counter-select maize plants with decreased ear weight and decreased yield.
    Type: Application
    Filed: September 11, 2015
    Publication date: October 26, 2017
    Inventors: Steven R. Anderson, Ada S. Ching, Stanley Luck, J. Antoni Rafalski
  • Publication number: 20160355834
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the the polypeptide involved in post-transcriptional gene silencing.
    Type: Application
    Filed: August 23, 2016
    Publication date: December 8, 2016
    Inventors: Rebecca E. Cahoon, HAJIME SAKAI, J ANTONI RAFALSKI
  • Patent number: 9453236
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: September 27, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Rebecca E. Cahoon, Hajime Sakai, J. Antoni Rafalski
  • Patent number: 9228241
    Abstract: The invention relates to methods and compositions for identifying and for selecting maize plants with mechanical stalk strength characteristics. The methods use molecular markers to identify and select plants with increased mechanical stalk strength or to identify and counter-select plants with decreased mechanical stalk strength. Maize plants generated by the methods of the invention are also a feature of the invention.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: January 5, 2016
    Assignees: E I DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL INC
    Inventors: Marymar Goncalves Butruille, Ada S Ching, Stanley Luck, J Antoni Rafalski
  • Publication number: 20150197821
    Abstract: A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyses of the genome are used to predict the degree of a heterotic phenotype in plants. In some examples, copy number variation is used to predict the degree of heterotic phenotype. In some methods copy number variation is detected using competitive genomic hybridization arrays. Further, methods for optimizing the arrays are disclosed, together with kits for producing such arrays, as well as hybrid plants selected for development based on the predicted results.
    Type: Application
    Filed: March 20, 2015
    Publication date: July 16, 2015
    Applicant: E.I. du Pont de Nemours and Company
    Inventors: Mary BEATTY, James A. JANNI, Jonathan E. LIGHTNER, J. Antoni RAFALSKI
  • Patent number: 8996318
    Abstract: A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyzes of the genome are used to predict the degree of a heterotic phenotype in plants. In some examples, copy number variation is used to predict the degree of heterotic phenotype. In some methods copy number variation is detected using competitive genomic hybridization arrays. Further, methods for optimizing the arrays are disclosed, together with kits for producing such arrays, as well as hybrid plants selected for development based on the predicted results.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: March 31, 2015
    Assignees: Pioneer Hi-Bred International, Inc., E. I. du Pont de Nemours and Company
    Inventors: Mary Beatty, James A. Janni, Jonathan E. Lightner, J. Antoni Rafalski
  • Patent number: 8900808
    Abstract: The invention relates to methods and compositions for identifying and for selecting maize plants with mechanical stalk strength characteristics. The methods use molecular markers to identify and select plants with increased mechanical stalk strength or to identify and counter-select plants with decreased mechanical stalk strength. Maize plants generated by the methods of the invention are also a feature of the invention.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: December 2, 2014
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Ada Ching, J. Antoni Rafalski, Stanley Luck, Marymar Goncalves Butruille
  • Publication number: 20140259217
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Application
    Filed: May 22, 2014
    Publication date: September 11, 2014
    Applicant: E I Du Pont De Nemours And Company
    Inventors: Rebecca E Cahoon, Hajime Sakai, J Antoni Rafalski
  • Patent number: 8748697
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: June 10, 2014
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Rebecca E. Cahoon, Hajime Sakai, J. Antoni Rafalski
  • Publication number: 20140130206
    Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: January 10, 2014
    Publication date: May 8, 2014
    Applicants: PIONEER HI-BRED INTERNATIONAL INC, E I DU PONT DE NEMOURS AND COMPANY
    Inventors: EDGAR B. CAHOON, REBECCA E. CAHOON, SAVERIO CARL FALCO, YIWEN FANG, SABINE S. HANTKE, ANTHONY J. KINNEY, JIAN-MING LEE, ZHONGSEN LI, GUO-HUA MIAO, MICHELE MORGANTE, XIPING NIU, JOAN T. ODELL, J ANTONI RAFALSKI, HAJIME SAKAI, PEIZHONG ZHENG, QUINN QUN ZHU
  • Publication number: 20130266945
    Abstract: The invention relates to methods and compositions for identifying and for selecting maize plants with mechanical stalk strength characteristics. The methods use molecular markers to identify and select plants with increased mechanical stalk strength or to identify and counter-select plants with decreased mechanical stalk strength. Maize plants generated by the methods of the invention are also a feature of the invention.
    Type: Application
    Filed: June 10, 2013
    Publication date: October 10, 2013
    Inventors: MARYMAR GONCALVES BUTRUILLE, Ada S. Ching, Stanley Luck, J. Antoni Rafalski
  • Publication number: 20130007912
    Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 3, 2013
    Applicant: EI DU PONT DE NEMOURS AND COMPANY; AND PIONEER HI-BRED INTERNATIONAL INC
    Inventors: Quinn Qun Zhu, Sabine S. Hantke, Xiping Niu, Zheng Peihong, Michele Morgante, Joan T. Odell, Saverio Carl Falco, Yiwen Fang, J. Antoni Rafalski, Hajime Sakai, Edgar B. Cahoon, Rebecca E. Cahoon, Jian-Ming Lee, Guo-Hua Miao, Zhongsen Li, Anthony J. Kinney
  • Publication number: 20120331581
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Application
    Filed: August 27, 2012
    Publication date: December 27, 2012
    Inventors: Rebecca E. Cahoon, Hajime Sakai, J. Antoni Rafalski
  • Patent number: 8288616
    Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: October 16, 2012
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Edgar Benjamin Cahoon, Rebecca E. Cahoon, Saverio Carl Falco, Yiwen Fang, Sabine S. Hantke, Anthony J. Kinney, Jian-Ming Lee, Zhongsen Li, Guo-Hua Miao, Michele Morgante, Xiping Niu, Joan T. Odell, J. Antoni Rafalski, Hajime Sakai, Peizhong Zheng, Quinn Qun Zhu
  • Patent number: 8278431
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: October 2, 2012
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Rebecca E. Cahoon, Hajime Sakai, J. Antoni Rafalski
  • Publication number: 20110321189
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 29, 2011
    Inventors: Rebecca E. Cahoon, J. Antoni Rafalski, Hajime Sakai
  • Patent number: 8022196
    Abstract: This invention relates to isolated nucleic acid fragments encoding polypeptides involved in post-transcriptional gene silencing. The invention also relates to construction of a recombinant DNA construct encoding all or a portion of the polypeptide involved in post-transcriptional gene silencing, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels in a transformed host cell of the polypeptide involved in post-transcriptional gene silencing.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: September 20, 2011
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Rebecca E. Cahoon, Hajime Sakai, J. Antoni Rafalski