Abstract: Described herein are interleukin-18 receptor binding moieties and uses thereof. An interleukin-18 receptor binding moiety can be an interleukin-18 receptor agonist or antagonist. An interleukin-18 receptor agonist can be an interleukin-18 receptor alpha binding moiety, an interleukin-18 receptor beta binding moiety, or can include interleukin-18 receptor alpha binding moiety and an interleukin-18 receptor beta binding moiety. An interleukin-18 receptor antagonist can be an interleukin-18 receptor alpha binding moiety, an interleukin-18 receptor beta binding moiety, or can include interleukin-18 receptor alpha binding moiety and an interleukin-18 receptor beta binding moiety. Interleukin-18 receptor agonists and interleukin-18 receptor antagonists can be formulated in a pharmaceutical formulation.

Abstract: A system and method in accordance with example embodiments for comprehensive sales and service data reporting. Sales and service events that take place at a front end branch of an enterprise may be input into a front end system and transmitted to a backend system where various modules then use the front end system data to generate various data and reports to display various data, such as, for example, sales incentive metrics and key performance indicators.

Abstract: IL-7R??c binding compounds and pharmaceutical compositions comprising the IL-7R??c binding compounds are disclosed. IL-7R??c bonding compounds can act as IL-7R agonists and are useful in treating cancer, viral diseases, autoimmune diseases, and inflammatory diseases.

Abstract: The use of IL-7R??c agonist peptides in cell manufacturing is disclosed. The IL-7R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-7R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: The use of IL-2R??c agonist peptides in cell manufacturing is disclosed. The IL-2R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-2R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: An electronic device may have a display mounted in a housing. The display may have a pixel array that produces images. A display cover layer may overlap the pixel array. The display cover layer may have a planar central area surrounded by a peripheral edge area with a curved cross-sectional profile. From an on-axis viewing angle, an image on the pixel array is fully viewable through the planar central area and the peripheral edge area. From an off-axis viewing angle, the image is partly viewable through the peripheral edge area and not through the central area. To avoid an undesired color cast in the partly viewable image seen through the peripheral edge area of the display cover layer, the display may be provided with color cast compensation structures such as a guest-host liquid crystal layer that exhibits an anisotropic colored light absorption characteristic, a diffuser layer, and/or other optical structures.

Abstract: An orthopaedic surgical instrument includes a patella trial and drill guide that may be used to both perform a surgical trial of the patellofemoral joint and guide the surgeon in drilling a number of anchor holes in the patella of the patient.

Abstract: An electronic device may have a display mounted in a housing. The display may have a pixel array that produces images. A display cover layer may overlap the pixel array. The display cover layer may have a planar central area surrounded by a peripheral edge area with a curved cross-sectional profile. From an on-axis viewing angle, an image on the pixel array is fully viewable through the planar central area and the peripheral edge area. From an off-axis viewing angle, the image is partly viewable through the peripheral edge area and not through the central area. To avoid an undesired color cast in the partly viewable image seen through the peripheral edge area of the display cover layer, the display may be provided with color cast compensation structures such as a guest-host liquid crystal layer that exhibits an anisotropic colored light absorption characteristic, a diffuser layer, and/or other optical structures.

Abstract: One embodiment is a remote display system. Embodiments include a liquid-crystal display (“LCD”), an outer surface that forms a gap between the outer surface and the LCD, a light sensor disposed within the gap and covering a portion of the LCD, and a flexible printed circuit board (“PCB”) that couples the light sensor to a server.

Abstract: A system for delivering energy to a patient's body includes a plurality of probes, a touch-sensitive display screen, and a controller communicatively coupled to each of the probes and the display screen. The controller is configured to perform operations including displaying a plurality of dynamically sized channel control regions within a user interface of the touch-sensitive display screen. Each of the plurality of channel control regions corresponds with at least one of the plurality of probes and is sized based at least in part on a number of the plurality of probes. The operations can include detecting a user touch action directed to a user-selected channel control region of the plurality of dynamically sized channel control regions. The operations can include performing a control action associated with the probe(s) that correspond with the user-selected channel control region when the user touch action is detected.

Abstract: One embodiment is a point of sale system that includes a head unit and an input output (I/O) unit coupled to the head unit and coupled to a network. The I/O unit includes a first controller adapted to, in response to a wake up event received from the network, generating a wake up message and transmitting the wake up message to the head unit. The head unit includes a second controller and a processor, the second controller adapted to receive the wake up message and in response generate a power on signal to the processor.

Abstract: A system for delivering energy to a patient's body is disclosed that includes a plurality of probes, a touch-sensitive display screen, and a controller communicatively coupled to each of the probes and the display screen. The controller is configured to perform operations including displaying a virtual control object in the user interface of the touch-sensitive display screen that is associated with an operating parameter of a treatment procedure performed with the probe. The controller is configured to adjust the operating parameter when a user touch action is directed to the virtual control object. The controller is configured to convert the virtual control object into a non-control label based, at least in part, on a current status of the treatment procedure. The controller is configured to prohibit adjustment of the operating parameter using the non-control label in response to a user touch action that is directed to the non-control label.

Abstract: A dispersive return pad for a radiofrequency ablation procedure includes a skin material adapted to be worn on a patient's skin, a conductive material positioned adjacent to the skin material, a non-conductive material surrounding the conductive material, and a phase-change material surrounding at least a portion of a side edge of the conductive material. Further, the phase-change material is configured to undergo a phase transition at a target temperature range corresponding to a non-damaging hyperthermic temperature range for the patient's skin. As such, the phase-change material is configured to absorb excess heating from the RF ablation procedure and to prevent burns to the patient's skin.

Abstract: A planned resource allocation data store may contain electronic records representing a plurality of planned resource allocations for an enterprise. An actual resource allocation data store may contain electronic records representing a plurality of actual resource allocations. A back-end application computer server may receive, from a remote user device associated with a first user identifier, data about planned and actual resource allocations and update the data stores. The computer server may also receive an indication of a period of time to be analyzed and access information in the planned and actual resource allocation data stores associated with the first user identifier and the period of time. A total planned occupancy value and a total actual occupancy value may then be calculated and displayed via an interactive user interface based on the accessed information.

Abstract: Pump assemblies and systems are provided. For example, a pump assembly comprises a pump head, a bezel surrounding an outer perimeter of the pump head, a motor, and tubing. The bezel comprises a bezel upper side, a bezel lower side opposite the bezel upper side, a bezel inlet side extending from the bezel upper side to the bezel lower side, and a bezel outlet side opposite the bezel inlet side and extending from the bezel upper side to the bezel lower side. The bezel defines an inlet channel on the bezel inlet side and an outlet channel on the bezel outlet side, each of the inlet channel and the outlet channel guiding the tubing into the pump head. An exemplary pump system comprises a plurality of pump assemblies that each supply a fluid to a cooling circuit and a base for supporting the plurality of pump assemblies.

Abstract: A system for delivering energy to a patient's body includes a plurality of probes, a touch-sensitive display screen, and a controller communicatively coupled to each of the probes and the display screen. The controller is configured to perform operations including displaying a plurality of dynamically sized channel control regions within a user interface of the touch-sensitive display screen. Each of the plurality of channel control regions corresponds with at least one of the plurality of probes and is sized based at least in part on a number of the plurality of probes. The operations can include detecting a user touch action directed to a user-selected channel control region of the plurality of dynamically sized channel control regions. The operations can include performing a control action associated with the probe(s) that correspond with the user-selected channel control region when the user touch action is detected.

Abstract: Pump heads for peristaltic pump assemblies are provided. For example, a pump head for a peristaltic pump comprises an occlusion bed, a rotor guide, a rotor assembly positioned between the occlusion bed and the rotor guide, and a pathway for tubing. The pathway comprises an inlet portion, an outlet portion, and a connecting portion that connects the inlet and outlet portions. The inlet portion is defined between the occlusion bed and the rotor guide, the outlet portion is defined between the occlusion bed and the rotor guide, and the connecting portion is defined between the occlusion bed and the rotor assembly. Further, the occlusion bed is movable with respect to the rotor guide and the rotor assembly. In exemplary embodiments, the pump head urges fluid flow through the tubing to supply a cooling fluid to a medical probe assembly for delivering energy to a patient's body.

Abstract: A planned resource allocation data store may contain electronic records representing a plurality of planned resource allocations for an enterprise. An actual resource allocation data store may contain electronic records representing a plurality of actual resource allocations. A back-end application computer server may receive, from a remote user device associated with a first user identifier, data about planned and actual resource allocations and update the data stores. The computer server may also receive an indication of a period of time to be analyzed and access information in the planned and actual resource allocation data stores associated with the first user identifier and the period of time. A total planned occupancy value and a total actual occupancy value may then be calculated and displayed via an interactive user interface based on the accessed information.

Abstract: Described are coated food products having a sugar (sucrose) coating, the coating exhibiting desirable levels of sucrose crystallinity and a desired sucrose ratio (total sucrose per total soluble solids), as well as methods or preparing such coated food products and coating.

Abstract: A method for operating a surgical device, includes: determining whether a switch has transitioned from a first condition, corresponding to a first operating mode, to a second condition, corresponding to a second operating mode; when it is determined that the switch has transitioned from the first condition to the second condition: maintaining the first operating mode for a pre-determined time; in a case where the switch remains in the second condition throughout the pre-determined time, switching to the second operating mode after expiration of the pre-determined time; and when the switch returns to the first condition during the pre-determined time, maintaining the first operating mode after expiration of the pre-determined time.